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108 results

Ovine trophoblasts express cathelicidin host defence peptide in response to infection

Journal Article
Coyle, C., Wheelhouse, N., Jacques, M., Longbottom, D., Svoboda, P., Pohl, J., …Barlow, P. G. (2016)
Ovine trophoblasts express cathelicidin host defence peptide in response to infection. Journal of Reproductive Immunology, 117, 10-16. https://doi.org/10.1016/j.jri.2016.06.006
Cationic host defence peptides (CHDP; also known as antimicrobial peptides) are key components of the immune response in the female reproductive tract. The role of the placent...

Antiviral host defence peptides.

Book Chapter
Sousa, F. H., Casanova, V., Stevens, C., & Barlow, P. G. (2016)
Antiviral host defence peptides. In R. M. Epand (Ed.), Host Defense Peptides and Their Potential as Therapeutic Agents, 57-94. Springer Verlag. https://doi.org/10.1007/978-3-319-32949-9_3
The on going global mortality and morbidity associated with viral pathogens highlights the need for the continued development of effective, novel antiviral molecules. The anti...

Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial

Journal Article
Hall, L., Farrington, A., Mitchell, B. G., Barnett, A. G., Halton, K., Allen, M., …Graves, N. (2016)
Researching effective approaches to cleaning in hospitals: protocol of the REACH study, a multi-site stepped-wedge randomised trial. Implementation Science, 11(1), https://doi.org/10.1186/s13012-016-0406-6
Background The Researching Effective Approaches to Cleaning in Hospitals (REACH) study will generate evidence about the effectiveness and cost-effectiveness of a novel cleanin...

Missing a trick? Response to: ‘Disinfectant wipes are appropriate to control microbial bioburden from surfaces’

Journal Article
Dancer, S. (2016)
Missing a trick? Response to: ‘Disinfectant wipes are appropriate to control microbial bioburden from surfaces’. Journal of Hospital Infection, 92(2), 208-209. https://doi.org/10.1016/j.jhin.2015.10.020
Letter to Editor. Refers to - J.-Y. Maillard, S.A. Sattar, C. Bradley Missing a trick? Response to: ‘Disinfectant wipes are appropriate to control microbial bioburden from su...

Effect of Ozone Treatment on Inactivation of Escherichia coli and Listeria sp. on Spinach

Journal Article
Wani, S., Maker, J., Thompson, J., Barnes, J., & Singleton, I. (2015)
Effect of Ozone Treatment on Inactivation of Escherichia coli and Listeria sp. on Spinach. Agriculture, 5(2), 155-169. https://doi.org/10.3390/agriculture5020155
The efficacy of “gaseous” ozone in reducing numbers and re-growth of food-borne pathogens, (Escherichia coli and Listeria spp.), on leafy salads was investigated using spinach...

Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status

Journal Article
Prach, M., Stone, V., & Proudfoot, L. (2012)
Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status. Toxicology and Applied Pharmacology, 266(1), 19-26. https://doi.org/10.1016/j.taap.2012.10.020
Zinc oxide (ZnO) particle induced cytotoxicity was dependent on size, charge and solubility, factors which at sublethal concentrations may influence the activation of the huma...

Regulation of capsule expression

Book Chapter
Taylor, C., & Roberts, I. S. (2010)
Regulation of capsule expression. In . M. Wilson (Ed.), Bacterial Adhesion to Host Tissues: Mechanisms and Consequences, (115-138). Cambridge: Cambridge University Press
No abstract available.

Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death: DAPK and signal transduction

Journal Article
Lin, Y., Hupp, T. R., & Stevens, C. (2009)
Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death: DAPK and signal transduction. FEBS Journal, 277(1), (48-57). ISSN 1742-464X
Death-associated protein kinase (DAPK) is a stress-regulated protein kinase that mediates a range of processes, including signal-induced cell death and autophagy. Although the...

ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1: ATP stimulated inhibition of E2F1 by MDM2

Journal Article
Stevens, C., Pettersson, S., Wawrzynow, B., Wallace, M., Ball, K., Zylicz, A., & Hupp, T. R. (2008)
ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1: ATP stimulated inhibition of E2F1 by MDM2. FEBS Journal, 275(19), 4875-4886. https://doi.org/10.1111/j.1742-4658.2008.06627.x
Murine double minute 2 (MDM2) protein exhibits many diverse biochemical functions on the tumour suppressor protein p53, including transcriptional suppression and E3 ubiquitin ...

The human lifespan and its effect on selecting nursing interventions

Book Chapter
Tait, D. (2007)
The human lifespan and its effect on selecting nursing interventions. In C. Brooker, & A. Waugh (Eds.), Foundations of Nursing Practice (185-220). Elsevier
Book specifically written to meet the needs of nursing students undertaking a common foundation programme, explaining how and why sensitive, holistic and evidence-based nursin...
25 results

Development of a scale-up process for production of Kombucha

2022 - 2023
Gut Feelings main commercial product is Kombucha, a fermented tea produced by natural microbial fermentation and assumed to contain a variety of microbes that link to health benefits. It is produced u...
Funder: Scottish Funding Council | Value: £4,960

Virulence of diverse Listeria monocytogenes strains in an invertebrate infection model

2022 - 2022
Listeria monocytogenes (L. monocytogenes) is a bacterium which is found throughout the environment and is the cause of listeriosis, a major food-borne disease. While annual case numbers are relatively...
Funder: Medical Research Scotland | Value: £2,160

Quantifying AMR in the River Almond Catchment Area

2021 - 2025
Aim To Quantifying AMR Pollution and identify the major sources of point and diffuse AMR pollution in the River Almond Catchment Area in order to provide a baseline for future risk assessment and inte...
Funder: Natural Environment Research Council | Value: £52,080

Scotland-India Antimicrobial Resistance in the Environment Network (SIAMREN)

2020 - 2021
This project focuses upon the creation and growth of a network of researchers within Scotland and India who have common research interests in the challenges presented by the emergence of antimicrobial...
Funder: Royal Society of Edinburgh

The prevalence of antibiotic resistance pathogen E. coli in Scottish surface waters

2019 - 2023
The alarming rise in resistance to antibiotics is now widely accepted as being one of the most serious public health crises we face today. The use and overuse of antibiotics in human and animal medici...
Funder: Medical Research Scotland | Value: £129,161

The role of NamA in L. monocytogenes virulence gene expression

2019 - 2020
Student Placement Scholarship 2019. Provides up to 8 weeks of paid laboratory experience for an undergraduate student.
Funder: Society of Applied Microbiology | Value: £2,500

Bacteriophage endolysins and novel lipid-degrading proteins as a treatment for Rhodococcus equi infections in foals

2018 - 2019
Rhodococcus equi (Req) is responsible for severe respiratory disease of foals with a major economic impact on the equine industry, and can be endemic on stud farms. In foals under 6 months of age, thi...
Funder: Horserace Betting Levy Board | Value: £10,832

Rutherford fund Strategic Partner Grant

2018 - 2019
Rutherford Fellows, will work in project areas related to food safety (Pathogen detection, AMR etc) and food spoilage. Rutherford Fund, are funded by BEIS and the scheme is being managed by Universit...
Funder: Department for Business, Energy & Industrial Strategy | Value: £39,800

Direct and paracrine effects of Chlamydia infection on decidualisation of endometrial stromal cells

2018 - 2018
SRF summer studentship
Funder: Society for Reproduction and Fertility | Value: £2,750

TRANSFORM - Education reform project – Improving Research capability in the Sri Lankan Higher Education sector.

2018 - 2019
TRANSFORM - Education reform project – Improving Research capability in the Sri Lankan Higher Education sector.
Funder: British Council | Value: £75,000