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Optimizing polypharmacy management in the elderly: a comprehensive European benchmarking survey and the development of an innovative online benchmarking application

Journal Article
Kardas, P., Mair, A., Stewart, D., & Lewek, P. (2023)
Optimizing polypharmacy management in the elderly: a comprehensive European benchmarking survey and the development of an innovative online benchmarking application. Frontiers in Pharmacology, 14, Article 1254912. https://doi.org/10.3389/fphar.2023.1254912
Background: Polypharmacy, defined as the simultaneous use of multiple medications by a patient, is a worldwide problem of rising prevalence. Paving the way for drug interactio...

Optimizing pharmacotherapy and deprescribing strategies in older adults living with multimorbidity and polypharmacy: EuGMS SIG on pharmacology position paper

Journal Article
van Poelgeest, E., Seppala, L., Bahat, G., Ilhan, B., Mair, A., van Marum, R., …van der Velde, N. (2023)
Optimizing pharmacotherapy and deprescribing strategies in older adults living with multimorbidity and polypharmacy: EuGMS SIG on pharmacology position paper. European Geriatric Medicine, 14(6), 1195-1209. https://doi.org/10.1007/s41999-023-00872-0
Key summary points: Aim: To summarize the literature on medication review and deprescribing in older adults, and formulate recommendations to improve prescribing medications i...

Recommendations for wider adoption of clinical pharmacy in Central and Eastern Europe in order to optimise pharmacotherapy and improve patient outcomes

Journal Article
Urbańczyk, K., Guntschnig, S., Antoniadis, V., Falamic, S., Kovacevic, T., Kurczewska-Michalak, M., …Kardas, P. (2023)
Recommendations for wider adoption of clinical pharmacy in Central and Eastern Europe in order to optimise pharmacotherapy and improve patient outcomes. Frontiers in Pharmacology, 14, Article 1244151. https://doi.org/10.3389/fphar.2023.1244151
Clinical pharmacy as an area of practice, education and research started developing around the 1960s when pharmacists across the globe gradually identified the need to focus m...

Polypharmacy and Integrated Care

Book Chapter
Mair, A., & Alonso, A. (2021)
Polypharmacy and Integrated Care. In V. Amelung, V. Stein, E. Suter, N. Goodwin, E. Nolte, & R. Balicer (Eds.), Handbook Integrated Care (453-477). Cham: Springer. https://doi.org/10.1007/978-3-030-69262-9_27
Safe and effective pharmacological treatment remains one of the greatest challenges in medicine, where models of healthcare delivery lag behind the enormous growth in single d...

Appropriate polypharmacy: a barometer for integrated care

Journal Article
Mair, A., Antoniadou, E., Hendry, A., & Gabrovec, B. (2021)
Appropriate polypharmacy: a barometer for integrated care. Journal of Integrated Care, 29(2), 204-214. https://doi.org/10.1108/jica-04-2020-0019
Purpose Polypharmacy, the concurrent use of multiple medicines by one individual, is a common and growing challenge driven by an ageing population and the growing number of pe...

Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials

Journal Article
Pazan, F., Petrovic, M., Cherubini, A., Onder, G., Cruz-Jentoft, A. J., Denkinger, M., …Wehling, M. (2021)
Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials. European Journal of Clinical Pharmacology, 77(1), 1-12. https://doi.org/10.1007/s00228-020-02951-8
Background Frailty and adverse drug effects are linked in the fact that polypharmacy is correlated with the severity of frailty; however, a causal relation has not been proven...

Addressing the Challenge of Polypharmacy

Journal Article
Mair, A., Wilson, M., & Dreischulte, T. (2020)
Addressing the Challenge of Polypharmacy. Annual Review of Pharmacology and Toxicology, 60(1), 661-681. https://doi.org/10.1146/annurev-pharmtox-010919-023508
Polypharmacy describes the concomitant use of multiple medicines and represents a growing global challenge attributable to aging populations with an increasing prevalence of m...

Quality Prescribing for Chronic Pain: A Guide for Improvement

Report
Chronic Pain Expert group, , & Scottish Government, . (2019)
Quality Prescribing for Chronic Pain: A Guide for Improvement. Edinburgh: Scottish Government

Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

Journal Article
Bousquet, J. J., the ARIA Study Group, , Schünemann, H. J., Togias, A., Erhola, M., Hellings, P. W., …the MASK Study Group, . (2019)
Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases. Clinical and Translational Allergy, 9, https://doi.org/10.1186/s13601-019-0279-2
Background In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health ca...

The polypharmacy programme in Scotland: realistic prescribing

Journal Article
Mair, A., Wilson, M., & Dreischulte, T. (2019)
The polypharmacy programme in Scotland: realistic prescribing. Prescriber, 30(8), 10-16. https://doi.org/10.1002/psb.1779
Since 2012, NHS Scotland has published a series of polypharmacy guidelines to help clinicians address the many medication‐related problems arising from multimorbidity. Here, A...