Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men
Journal Article
Ross, M., Ingram, L., Taylor, G., Malone, E., Simpson, R. J., West, D., & Florida-James, G. (2018)
Older men display elevated levels of senescence-associated exercise-responsive CD28null angiogenic T cells compared with younger men. Physiological Reports, 6(12), 1-11. https://doi.org/10.14814/phy2.13697
Aging is associated with elevated cardiovascular disease risk. As a result of aging, endothelial dysfunction develops, partly due to a reduction in vascular regenerative abili...
The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults
Journal Article
Lithgow, H. M., Florida-James, G., & Leggate, M. (2018)
The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults. Physiological Reports, 6(9), https://doi.org/10.14814/phy2.13684
High intensity intermittent training (HIIT) has been shown to reduce the risk of chronic conditions including the development of type 2 diabetes mellitus (T2DM). Independently...
Anticipation and the cortisol awakening response within a dynamic psychosocial work environment
Journal Article
Campbell, T. G., Westbury, T., Davison, R., & Florida-James, G. (2018)
Anticipation and the cortisol awakening response within a dynamic psychosocial work environment. International Journal of Stress Prevention and Wellbeing, 2,
The cortisol awakening response (CAR) is a distinct element of the diurnal pattern of cortisol release, believed to be partly driven by the anticipation of the demands of the ...
Physiological characteristics and performance in elite enduro mountain biking
Journal Article
Kirkwood, L., Ingram, L., Cunningham, J., Malone, E., & Florida-James, G. (2017)
Physiological characteristics and performance in elite enduro mountain biking. Journal of Science and Cycling, 6(2), 13-21. https://doi.org/10.28985/171231.jsc.09
Enduro mountain bike racing is composed of several timed predominantly downhill race stages linked by time restricted, non-competitive transition stages. This study aimed to ...
Lower Resting and Exercise-Induced Circulating Angiogenic Progenitors and Angiogenic T-Cells in Older Men
Journal Article
Ross, M. D., Malone, E. M., Simpson, R., Cranston, I., Ingram, L., Wright, G. P., …Florida-James, G. D. (2018)
Lower Resting and Exercise-Induced Circulating Angiogenic Progenitors and Angiogenic T-Cells in Older Men. American journal of physiology. Heart and circulatory physiology, 314(3), 392-402. https://doi.org/10.1152/ajpheart.00592.2017
Ageing is associated with a dysfunctional endothelial phenotype, as well as reduced angiogenic capabilities. Exercise exerts beneficial effects on the cardiovascular system, p...
Vascular Ageing and Exercise: Focus on Cellular Reparative Processes
Journal Article
Ross, M. D., Malone, E., & Florida-James, G. (2016)
Vascular Ageing and Exercise: Focus on Cellular Reparative Processes. Oxidative Medicine and Cellular Longevity, 2016, 1-15. https://doi.org/10.1155/2016/3583956
Ageing is associated with an increased risk of developing noncommunicable diseases (NCDs), such as diabetes and cardiovascular disease (CVD). The increased risk can be attribu...
A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males: Acute exercise mobilizes angiogenic T cells
Journal Article
Ross, M., Tormey, P., Ingram, L., Simpson, R., Malone, E., & Florida-James, G. (2016)
A 10 km time trial running bout acutely increases the number of angiogenic T cells in the peripheral blood compartment of healthy males: Acute exercise mobilizes angiogenic T cells. Experimental Physiology, 101(10), 1253-1264. https://doi.org/10.1113/ep085771
New Findings
What is the central question of the study?
Are CD31+ angiogenic T (TANG) cells preferentially mobilized in response to acute exercise?
What is the main finding an...
Blood lactate thresholds and walking/running economy are determinants of backpack-running performance in trained soldiers
Journal Article
Simpson, R. J., Graham, S. M., Connaboy, C., Clement, R., Pollonini, L., & Florida-James, G. D. (2017)
Blood lactate thresholds and walking/running economy are determinants of backpack-running performance in trained soldiers. Applied Ergonomics, 58, 566-572. https://doi.org/10.1016/j.apergo.2016.04.010
We developed a standardized laboratory treadmill protocol for assessing physiological responses to a simulated backpack load-carriage task in trained soldiers, and assessed th...
Letter regarding article: ‘Effect of acute exercise on circulating angiogenic cell and microparticle populations’: Letter to the Editor
Journal Article
Ross, M., Ingram, L., Tormey, P., & Florida-James, G. (2016)
Letter regarding article: ‘Effect of acute exercise on circulating angiogenic cell and microparticle populations’: Letter to the Editor. Experimental Physiology, 101(4), 558-558. https://doi.org/10.1113/ep085700
No abstract available. Item is letter to the editor.
Exercise and the Immune System
Book Chapter
Gomes, E. C., & Florida-James, G. (2016)
Exercise and the Immune System. In C. Esser (Ed.), Environmental Influences on the Immune System (127-152). Vienna, Austria: Springer. https://doi.org/10.1007/978-3-7091-1890-0_6
This chapter is divided into three major parts. The first part covers how exercise is associated with respiratory infection. Exercise’s effect on mucosal immunity, allergic rh...