CPTSD and Psychosis: Psychological Interventions for Complex PTSD And Schizophrenia-Spectrum disOrder (PICASSO)
  Psychosis is a highly distressing mental health condition, affecting up to 3% of the population. Conceptually, it has much in common with complex post-traumatic stress disorder (CPTSD). Both involve negative self-esteem, impaired emotion regulation ability, interpersonal difficulties and intrusive trauma-related experiences (intrusive thoughts, flashbacks, nightmares). Both have been causally related to childhood trauma, such as abuse, neglect and loss. The current project will examine the feasibility of conducting an ‘Umbrella trial’ to test whether CPTSD is causally related to psychosis, and develop more effective trauma-focused psychological interventions for psychotic symptoms by treating underlying experiences of/reactions to trauma. An Umbrella trial involves running several individual randomised controlled trials concurrently. In this study, each will test whether psychological interventions designed to reduce different CPTSD symptoms causes improvements in psychotic symptoms. If we can establish feasibility of this Umbrella trial, and if a definitive version shows that interventions for CPTSD also reduce psychosis, then this would be a breakthrough in both the conceptualisation and treatment of this distressing condition.

  • Start Date:

    1 January 2022

  • End Date:

    30 November 2023

  • Activity Type:

    Externally Funded Research

  • Funder:

    Chief Scientists Office

  • Value:


Project Team