Giacomo Russo
giacomo russo

Dr Giacomo Russo FHEA, MRSC, Pharm.D., MSc

Lecturer

Biography

Dr. Giacomo Russo achieved in 2012 a master’s degree in “Chemistry and Pharmaceutical Technology” summa cum laude from University of Naples Federico II. In 2013, he was kindly asked to join the Pharm-Analysis & Bio-Pharm Laboratory from the same University for a Ph.D. in Pharmaceutical Sciences, which he completed (grade: Excellent) in 2016. During his Ph.D. studies, he worked for three months in 2015 as visiting Ph.D. candidate at the Drug Design Laboratories of the University of Milan “Statale” headed by Prof. Dr. Alessandro Pedretti and Prof. Dr. Giulio Vistoli, where he got hand-on experience and practical training in Computational Chemistry and Chemometrics. At the end of the same year, he was accepted as visiting Ph.D. candidate at the Separation Science Group (SSG), University of Ghent (UGent) (Belgium) for conducting biopartitioning studies for seven months in the state-of-the-art analytical laboratories led by Prof. Frederic Lynen. Dr. Giacomo Russo conducted post-doctoral research in nanoplasmonics and microcalorimetry at the Department of Chemistry, University of Helsinki (Finland) for 5 months in 2016 with the supervision of Prof. Dr. Susanne Kristina Wiedmer. He then was involved in other postdoctoral studies in formulation of a novel manganese superoxide dismutase with antitumoral activity in highly selective and biocompatible polymeric assemblies. This project was a joint activity involving the University of Palermo (supervisor: Prof. Massimo Midiri), the Italian Institute of Technology (supervisor: Ing. Raffaele Vecchione) and the University of Naples Federico II (supervisor: Prof. Lucia Grumetto). From August 2018, Dr. Russo joined again the SSG for innovative research concerning 3D printing and multidimensional gas and liquid chromatography for 1.5 years. After 3 and half year from the completion of his Ph.D., Dr. Giacomo Russo got a permanent lectureship in Pharmaceutical Sciences at Edinburgh Napier University, Edinburgh (UK). Dr. Russo currently co-authored 39 original papers, 1 review article, 9 posters and gave 13 oral communications at national and international conferences. He got 4 awards (of which 2 best poster awards). He is also active as reviewer (average 1 paper/month from Pharmaceutical Sciences and Analytical Chemistry journals) and expert for the National Science Poland (call PRELUDIUM). He was included in December 2019 in the list of Rising Stars of Separation Science by the journal LC GC Europe.

Esteem

Membership of Professional Body

  • The Chromatographic Society
  • The Royal Society of Chemistry
  • The Academy of Pharmaceutical Sciences

 

Date


46 results

Synergism between bisphenol a exposure and overweight/obesity in increasing the malignancy risk in a cohort of patients with thyroid nodules

Journal Article
Marotta, V., Grumetto, L., Neri, I., Russo, G., Tortora, A., Izzo, G., …Vitale, M. (2022)
Synergism between bisphenol a exposure and overweight/obesity in increasing the malignancy risk in a cohort of patients with thyroid nodules. Endocrine abstracts, 81, Article P394. https://doi.org/10.1530/endoabs.81.p394
Introduction: The plasticizer Bisphenol A (BPA) is an endocrine disruptor with thyroid interfering activity. Obesity is a recognized risk factor for thyroid cancer. A recent s...

Modeling the blood brain barrier permeation of drugs by biomimetic liquid chromatography

Presentation / Conference
Russo, G. (2022, March)
Modeling the blood brain barrier permeation of drugs by biomimetic liquid chromatography. Presented at 1st Scotland - Rheinland-Pfalz Life Sciences and Biotechnology Conference, Online

cΔlog kwIAM: can we afford estimation of small molecules’ blood-brain barrier passage based upon in silico phospholipophilicity?

Journal Article
Grumetto, L., & Russo, G. (2021)
cΔlog kwIAM: can we afford estimation of small molecules’ blood-brain barrier passage based upon in silico phospholipophilicity?. ADMET and DMPK, 9(4), 267-281. https://doi.org/10.5599/admet.1034
56 compounds, whose log BB values were known from the scientific literature, were considered and their phospholipophilicity values were calculated in silico. These values, alo...

Comprehensive 2D liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development

Presentation / Conference
Russo, G., Grumetto, L., Baert, M., & Lynen, F. (2021, June)
Comprehensive 2D liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development. Poster presented at Analytical Research Forum 2021, Royal Society of Chemistry, Online

Characterization of the new Celeris (TM) Arginine column: retentive behaviour through a combination of chemometric tools and potential in drug analysis

Journal Article
Russo, G., Vallaro, M., Cappelli, L., Anderson, S., Ermondi, G., & Caron, G. (2021)
Characterization of the new Celeris (TM) Arginine column: retentive behaviour through a combination of chemometric tools and potential in drug analysis. Journal of Chromatography A, 1651, https://doi.org/10.1016/j.chroma.2021.462316
CelerisTM Arginine (ARG) is a mixed-mode stationary phase recently released on the market. To characterize its analytical behavior, the retention factors of a pool (n=100, of ...

Prolonged activity of a recombinant manganese superoxide dismutase through a formulation of polymeric multi-layer nanoassemblies targeting cancer cells

Journal Article
Russo, G., Iaccarino, G., Piccolo, M., Ferraro, M. G., Vecchione, R., Grumetto, L., …Santamaria, R. (2021)
Prolonged activity of a recombinant manganese superoxide dismutase through a formulation of polymeric multi-layer nanoassemblies targeting cancer cells. European Journal of Pharmaceutical Sciences, 162, https://doi.org/10.1016/j.ejps.2021.105825
A new isoform of human manganese superoxide dismutase (SOD) has been recently isolated and obtained in a synthetic recombinant form and termed rMnSOD. As compared to other SOD...

The occurrence of selected endocrine‐disrupting chemicals in water and sediments from an urban lagoon in Southern Italy

Journal Article
Russo, G., Laneri, S., Di Lorenzo, R., Ferrara, L., & Grumetto, L. (2021)
The occurrence of selected endocrine‐disrupting chemicals in water and sediments from an urban lagoon in Southern Italy. Water Environment Research, 93(10), 1944-1958. https://doi.org/10.1002/wer.1566
Endocrine disrupting chemicals (EDCs) are agents able to exert perturbation toward the endocrine system via a broad array of signalling pathways. Some EDCs are released into t...

Emerging endocrine disruptors in two edible fish from the Persian Gulf: Occurrence, congener profile, and human health risk assessment

Journal Article
Akhbarizadeh, R., Russo, G., Rossi, S., Golianova, K., Moore, F., Guida, M., …Grumetto, L. (2021)
Emerging endocrine disruptors in two edible fish from the Persian Gulf: Occurrence, congener profile, and human health risk assessment. Marine Pollution Bulletin, 166, https://doi.org/10.1016/j.marpolbul.2021.112241
The occurrence of endocrine disrupting chemicals (EDCs) has been determined in two widely consumed fish species from Persian Gulf i.e., Epinephelus coioides and Platycephalus ...

Comprehensive two-dimensional liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development

Journal Article
Russo, G., Grumetto, L., Baert, M., & Lynen, F. (2021)
Comprehensive two-dimensional liquid chromatography as a biomimetic screening platform for pharmacokinetic profiling of compound libraries in early drug development. Analytica Chimica Acta, 1142, 157-168. https://doi.org/10.1016/j.aca.2020.11.003
A comprehensive two-dimensional liquid chromatography-based biomimetic platform (LCxLC) has been developed and validated for drug diffusion studies. Human serum albumin (HSA) ...

Into the first biomimetic sphingomyelin stationary phase: Suitability in drugs’ biopharmaceutic profiling and block relevance analysis of selectivity

Journal Article
Russo, G., Ermondi, G., Caron, G., Verzele, D., & Lynen, F. (2021)
Into the first biomimetic sphingomyelin stationary phase: Suitability in drugs’ biopharmaceutic profiling and block relevance analysis of selectivity. European Journal of Pharmaceutical Sciences, 156, 105585. https://doi.org/10.1016/j.ejps.2020.105585
State of the art: Sphingomyelin (SPH) is a type of sphingolipid found in animal nerve tissues, especially in the membranous myelin sheath that surrounds some nerve cell axons....