The effects of marathon running on expression of the complement regulatory proteins CD55 (DAF) and CD59 (MACIF) on red blood cells.
Journal Article
Simpson, R. J., Florida-James, G., Whyte, G. P., Middleton, N., Shave, R., George, K., & Guy, K. (2007)
The effects of marathon running on expression of the complement regulatory proteins CD55 (DAF) and CD59 (MACIF) on red blood cells. European Journal of Applied Physiology, 99, 201-204. https://doi.org/10.1007/s00421-006-0326-2
Exercise is known to result in the haemolysis of red blood cells (RBCs). Although mechanical stressors such as footstrike and an increased velocity of blood flow may be involv...
Immune alterations, lipid peroxidation, and muscle damage following a hill race.
Journal Article
Simpson, R. J., Wilson, M. R., Black, J., Ross, J. A., Whyte, G. P., Guy, K., & Florida-James, G. (2005)
Immune alterations, lipid peroxidation, and muscle damage following a hill race. Applied Physiology, Nutrition, and Metabolism, 30, 196-211. https://doi.org/10.1139/h05-115
Hill races usually include large downhill running sections, which can induce significant degrees of muscle damage in a field setting. This study examined the link between musc...
Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise
Journal Article
Simpson, R. J., Cosgrove, C., Ingram, L. A., Florida-James, G. D., Whyte, G. P., Pircher, H., & Guy, K. (2008)
Senescent T-lymphocytes are mobilised into the peripheral blood compartment in young and older humans after exhaustive exercise. Brain, Behavior, and Immunity, 22(4), 544-551. https://doi.org/10.1016/j.bbi.2007.11.002
Senescent T-lymphocytes are antigen-experienced cells that express the killer-cell lectin-like receptor G1 (KLRG1) and/or CD57; fail to clonally expand following further antig...
High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects.
Journal Article
Simpson, R. J., Florida-James, G., Cosgrove, C., Whyte, G. P., Macrae, S., Pircher, H., & Guy, K. (2007)
High-intensity exercise elicits the mobilization of senescent T lymphocytes into the peripheral blood compartment in human subjects. Journal of Applied Physiology, 103, 396-401. https://doi.org/10.1152/japplphysiol.00007.2007
Clonal expansion of T lymphocytes in response to antigenic stimulation is a fundamental process of adaptive immunity. As a consequence of clonal expansion, some T lymphocytes ...