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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Journal Article
Baghdiguian, S., Bagniewska-Zadworna, A., Baek, S., Baehrecke, E. H., Bae, S. H., Bae, D., …Stevens, C. (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), 1-222. https://doi.org/10.1080/15548627.2015.1100356
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientis...

Patient-derived measures of GI endoscopy: a meta-narrative review of the literature

Journal Article
Brown, S., Bevan, R., Rubin, G., Nixon, C., Dunn, S., Rees, C., …Rees, C. J. (2015)
Patient-derived measures of GI endoscopy: a meta-narrative review of the literature. Gastrointestinal Endoscopy, 81(5), 1130-1140. https://doi.org/10.1016/j.gie.2014.11.047
Background and Aims GI endoscopy (GIE) is widely performed, with 1 in 3 people requiring an endoscopic procedure at some point. Patient experience of medical procedures is imp...

Effects of etidronate on the Enpp1−/− mouse model of generalized arterial calcification of infancy

Journal Article
Huesa, C., Staines, K. A., Millán, J. L., & MacRae, V. E. (2015)
Effects of etidronate on the Enpp1−/− mouse model of generalized arterial calcification of infancy. International Journal of Molecular Medicine, 36(1), 159-165. https://doi.org/10.3892/ijmm.2015.2212
Generalized arterial calcification of infancy (GACI) is an autosomal recessive disorder of spontaneous infantile arterial and periarticular calcification which is attributed t...

Experiences of recruiting to a pilot trial of Cardiac Rehabilitation In patients with Bowel cancer (CRIB) with an embedded process evaluation: lessons learned to improve recruitment

Journal Article
Hubbard, G., Campbell, A., Davies, Z., Munro, J., Ireland, A. V., Leslie, S., …Treweek, S. (2015)
Experiences of recruiting to a pilot trial of Cardiac Rehabilitation In patients with Bowel cancer (CRIB) with an embedded process evaluation: lessons learned to improve recruitment. Pilot and Feasibility Studies, 1(1), https://doi.org/10.1186/s40814-015-0009-z
Background Recruitment to randomised controlled trials (RCTs) is a perennial problem. Calls have been made for trialists to make recruitment performance publicly available. Th...

PWE-090 the effect of commonly used Ibd drugs on autophagy induction using an in vitro cell culture system.

Journal Article
Henderson, P., Satsangi, J., Wilson, D., & Stevens, C. (2014)
PWE-090 the effect of commonly used Ibd drugs on autophagy induction using an in vitro cell culture system. Gut, 63(Suppl 1), A163. https://doi.org/10.1136/gutjnl-2014-307263.350
Introduction Genome wide association studies and functional experiments in inflammatory bowel disease (IBD) have delineated the importance of autophagy in IBD pathogenesis. We...

Predicting Carotid Artery Disease and Plaque Instability from Cell-derived Microparticles

Journal Article
Harrison, M., Wekesa, A., O'Donovan, O., O'Brien, O., Phelan, J., Ross, M., …Harrison, M. (2014)
Predicting Carotid Artery Disease and Plaque Instability from Cell-derived Microparticles. European Journal of Vascular and Endovascular Surgery, 48(5), 489-495. https://doi.org/10.1016/j.ejvs.2014.08.007
Objectives Cell-derived microparticles (MPs) are small plasma membrane-derived vesicles shed from circulating blood cells and may act as novel biomarkers of vascular disease. ...

Effects of supervised exercise on motivational outcomes in breast cancer survivors at 5-year follow-up

Journal Article
Trinh, L., Mutrie, N., Campbell, A. M., Crawford, J. J., & Courneya, K. S. (2014)
Effects of supervised exercise on motivational outcomes in breast cancer survivors at 5-year follow-up. European Journal of Oncology Nursing, 18(6), 557-563. https://doi.org/10.1016/j.ejon.2014.07.004
Short-term physical activity (PA) has beneficial effects on symptom management and quality of life, however, longer-term adherence is likely needed for improved disease outcom...

Type 2 diabetes mellitus and obesity in young adults: the extreme phenotype with early cardiovascular dysfunction

Journal Article
Wilmot, E. G., Leggate, M., Khan, J. N., Yates, T., Gorely, T., Bodicoat, D. H., …Davies, M. J. (2014)
Type 2 diabetes mellitus and obesity in young adults: the extreme phenotype with early cardiovascular dysfunction. Diabetic medicine : a journal of the British Diabetic Association, 31(7), 794-798. https://doi.org/10.1111/dme.12431
Aim A pilot study to phenotype young adults (Methods Twenty people with Type 2 diabetes (aged 18–40 years), 10 lean and 10 obese control subjects underwent detailed assessme...

Exercise intervention for patients surgically treated for Non-Small Cell Lung Cancer (NSCLC): A systematic review

Journal Article
Crandall, K., Maguire, R., Campbell, A., & Kearney, N. (2014)
Exercise intervention for patients surgically treated for Non-Small Cell Lung Cancer (NSCLC): A systematic review. Surgical Oncology, 23(1), 17-30. https://doi.org/10.1016/j.suronc.2014.01.001
AbstractBackground Surgery remains the best curative option for appropriately selected patients with lung cancer. Evidence suggests that improving cardiovascular fitness and f...

Understanding barriers to exercise implementation 5-year post-breast cancer diagnosis: a large-scale qualitative study

Journal Article
Hefferon, K., Murphy, H., McLeod, J., Mutrie, N., & Campbell, A. (2013)
Understanding barriers to exercise implementation 5-year post-breast cancer diagnosis: a large-scale qualitative study. Health Education Research, 28(5), 843-856. https://doi.org/10.1093/her/cyt083
Due to the amount of literature supporting exercise participation after cancer diagnosis, there has been recent interest in barriers to exercise engagement among cancer patien...