Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia
Journal Article
Dolan, S., Hastie, P. G. R., Crossan, C., & Nolan, A. M. (2011)
Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia. Molecular Pain, 7, 91. https://doi.org/10.1186/1744-8069-7-91
Background
This study characterised the effects of persistent peripheral inflammation of the foot on pain and spinal cord expression of cyclooxygenase-1 and -2 (COX-1 and COX...
NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy
Journal Article
Fox, S., Wilkinson, T. S., Wheatley, P. S., Xiao, B., Morris, R. E., Sutherland, A., …Rossi, A. G. (2010)
NO-loaded Zn2+-exchanged zeolite materials: A potential bifunctional anti-bacterial strategy. Acta biomaterialia, 6(4), (1515-1521). doi:10.1016/j.actbio.2009.10.038. ISSN 1742-7061
Nitric oxide (NO) is important for the regulation of a number of diverse biological processes, including vascular tone, neurotransmission, inflammatory cell responsiveness, de...
A questionnaire-based survey of perioperative blood conservation practice for revision hip arthroplasty in Scotland
Journal Article
Harkness, M., Palmer, J. B., Watson, D., & Walsh, T. S. (2008)
A questionnaire-based survey of perioperative blood conservation practice for revision hip arthroplasty in Scotland. Transfusion Medicine, 18, 296-301. https://doi.org/10.1111/j.1365-3148.2008.00883.x
The aim of this study was to describe current blood conservation practice during revision hip surgery in Scotland and document practice variation. Revision hip surgery is asso...
State changes in brain activity shown by the uptake of 99mTc-exametazime with single photon emission tomography in major depression before and after treatment
Journal Article
Goodwin, G. M., Austin, M., Dougall, N., Ross, M., Murray, C., O'Caroll, R. E., …Ebmeier, K. P. (1993)
State changes in brain activity shown by the uptake of 99mTc-exametazime with single photon emission tomography in major depression before and after treatment. Journal of Affective Disorders. 29(4), 243-253. doi:10.1016/0165-0327(93)90014-b. ISSN 0165-0327
Twenty-eight patients with a major depressive episode previously investigated at rest using Single Photon Emission Tomography (SPET or SPECT) with 99mTc-exametazime, were foll...
The intermediate filament protein, vimentin, is a regulator of NOD2 activity
Journal Article
Stevens, C., Henderson, P., Nimmo, E. R., Soares, D. C., Dogan, B., Simpson, K. W., …Satsangi, J. (2013)
The intermediate filament protein, vimentin, is a regulator of NOD2 activity. Gut, 62(5), 695-707. https://doi.org/10.1136/gutjnl-2011-301775
Objective Mutations in the nucleotide-binding oligomerisation domain-containing protein 2 (NOD2) gene remain the strongest genetic determinants for Crohn's disease (CD). Havin...
Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages
Journal Article
Li, H., Barlow, P. G., Bylund, J., Mackellar, A., Björstad, Å., Conlon, J., …Davidson, D. J. (2009)
Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages. Journal of Leukocyte Biology, 86(4), 891-902. https://doi.org/10.1189/jlb.0209050
Cathelicidins are CHDP with essential roles in innate host defense but also more recently associated with the pathogenesis of certain chronic diseases. These peptides have mic...