13 results

Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety

Journal Article
Morgenroth, E., Orlov, N., Lythgoe, D. J., Stone, J. M., Barker, H., Munro, J., …Allen, P. (2019)
Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety. Cortex, 117, 53-63. https://doi.org/10.1016/j.cortex.2019.02.021
Trait anxiety can affect cognitive control resulting in ineffective and/or inefficient task performance. Moreover, previous functional Magnetic Resonance Imaging (fMRI) studie...

Promoting student well-being: Are you better than you think?

Journal Article
Robertson, P. (2017)
Promoting student well-being: Are you better than you think?. Phoenix (AGCAS journal), 20-21
Dr Pete Robertson, Associate Professor & Programme Leader for Career Guidance in the School of Applied Sciences at Edinburgh Napier University, outlines proactive approaches t...

How evil people choose their victims: The Dark Triad and perceptions of personality traits and vulnerability

Presentation / Conference
Li Chung, K., Charles, K., Neill, C. & Willis, A. (2016, July)
How evil people choose their victims: The Dark Triad and perceptions of personality traits and vulnerability. Poster presented at 18th European Conference on Personality, Timișoara, Romania
The Dark Triad (DT) – Machiavellianism, narcissism, and psychopathy – is associated with grandiosity, insensitivity, and exploitation. Some people are found to be more sensiti...

A Randomized Controlled Evaluation of the Efficacy of an Ankle-Foot Cast on Walking Recovery Early After Stroke: SWIFT Cast Trial

Journal Article
Pomeroy, V. M., Rowe, P., Clark, A., Walker, A., Kerr, A., Chandler, E., …Ugboule, U. C. (2016)
A Randomized Controlled Evaluation of the Efficacy of an Ankle-Foot Cast on Walking Recovery Early After Stroke: SWIFT Cast Trial. Neurorehabilitation and Neural Repair, 30(1), 40-48. doi:10.1177/1545968315583724
Background. Timely provision of an ankle-foot orthosis (AFO) orthotist customized for individuals early after stroke can be problematic. Objective. To evaluate the efficacy of...

Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review

Journal Article
Graham, S. M., Baird, M., & Boyd, G. W. (2014)
Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review. Archives of Exercise in Health and Disease, 4(3), 286-298. https://doi.org/10.5628/aehd.v4i3.169
Parkinson’s disease (PD) is the second most common progressive neurodegenerative condition after Alzheimer’s Disease. It is characterized by a progressive loss of dopaminergic...

"I'm not insane, my mother had me tested." The risks and benefits of being labelled 'at-risk' for psychosis.

Journal Article
Welsh, P., & Brown, S. (2013)
"I'm not insane, my mother had me tested." The risks and benefits of being labelled 'at-risk' for psychosis. Health, Risk and Society, 15, 648-662. https://doi.org/10.1080/13698575.2013.848846
In this article we examine the identification of young people deemed to be at an elevated risk of developing psychosis (often referred to as an At-Risk Mental State for psycho...

Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease

Journal Article
Kerr, F., Augustin, H., Piper, M. D. W., Gandy, C., Allen, M. J., Lovestone, S., & Partridge, L. (2011)
Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease. Neurobiology of Aging, 32(11), 1977-1989. https://doi.org/10.1016/j.neurobiolaging.2009.10.015
Dietary restriction (DR) extends lifespan in diverse organisms and, in animal and cellular models, can delay a range of aging-related diseases including Alzheimer's disease (A...

Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease

Journal Article
Hye, A., Kerr, F., Archer, N., Foy, C., Poppe, M., Brown, R., …Lovestone, S. (2004)
Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease. Neuroscience Letters, 373(1), 1-4. https://doi.org/10.1016/j.neulet.2004.10.031
Alzheimer's disease (AD) is a disorder without a molecular marker in peripheral tissues or a disease modifying treatment. As increasing evidence has suggested a role for glyco...

Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor α1 and γ2 subunit gene cluster on chromosome 5

Journal Article
Sander, T., Hildmann, T., Janz, D., Wienker, T. F., Bianchi, A., Bauer, G., …Darlison, M. G. (1996)
Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor α1 and γ2 subunit gene cluster on chromosome 5. Epilepsy Research, 23(3), 235-244. https://doi.org/10.1016/0920-1211%2895%2900098-4
Hereditary factors play a major role in the etiology of idiopathic generalized epilepsies (IGEs). The pivotal function of ionotropic γ-aminobutyric acid type A receptors (GABR...

Schizophrenia and GABAA receptor subunit genes

Journal Article
Byerley, W., Bailey, M. E., Hicks, A. A., Riley, B. P., Darlison, M. G., Holik, J., …Coon, H. (1995)
Schizophrenia and GABAA receptor subunit genes. Psychiatric Genetics, 5(1), 23-30. https://doi.org/10.1097/00041444-199521000-00004
Alterations in γ-aminobutyric acid (GABA) neurotransmission have been indirectly implicated in the pathogenesis of schizophrenia. Using nine multiplex pedigrees, we tested for...