Alternative splicing increases GABA A receptor heterogeneity
Journal Article
Lasham, A., Bateson, A. N., & Darlison, M. G. (1991)
Alternative splicing increases GABA A receptor heterogeneity. Transactions, 19(1), 9S-9S. https://doi.org/10.1042/bst019009s
No abstract available.
The chicken GABA A receptor: heterogeneity of gamma subunits
Journal Article
Glencorse, T. A., Bateson, A. N., & Darlison, M. G. (1991)
The chicken GABA A receptor: heterogeneity of gamma subunits. Transactions, 19(1), 4S-4S. https://doi.org/10.1042/bst019004s
Amino acid receptors from insect muscle: electrophysiological characterization in Xenopus oocytes following expression by injection of mRNA
Journal Article
Fraser, S., Djamgoz, M., Usherwood, P., O'Brien, J., Darlison, M., & Barnard, E. (1990)
Amino acid receptors from insect muscle: electrophysiological characterization in Xenopus oocytes following expression by injection of mRNA. Molecular Brain Research, 8(4), 331-341. https://doi.org/10.1016/0169-328x%2890%2990047-h
Poly(A)+ messenger ribonucleic acid (mRNA) was extracted from leg muscles of the locust Schistocerca gregaria and injected into oocytes of Xenopus laevis. After 5–10 days incu...
Cloning of genomic and cDNA sequences encoding an invertebrate γ-aminobutyric acid A receptor subunit
Journal Article
Harvey, R. J., Vreugdenhill, E., Barnard, E. A., & Darlison, M. G. (1990)
Cloning of genomic and cDNA sequences encoding an invertebrate γ-aminobutyric acid A receptor subunit. Transactions, 18(3), 438-439. https://doi.org/10.1042/bst0180438
No abstract available.
Distinct regional expression of nicotinic acetylcholine receptor genes in chick brain
Journal Article
Morris, B. J., Hicks, A. A., Wisden, W., Darlison, M. G., Hunt, S. P., & Barnard, E. A. (1990)
Distinct regional expression of nicotinic acetylcholine receptor genes in chick brain. Molecular Brain Research, 7(4), 305-315. https://doi.org/10.1016/0169-328x%2890%2990081-n
Four genes (α2, α3, α4 and β2) have been reported as encoding subunits of the nicotinic acetylcholine receptor (nAChR) in chicken brain. The mRNAs transcribed from these genes...
The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies
Book Chapter
Darlison, M. G., Barnard, E. A., Bateson, A. N., Glencorse, T. A., Harvey, R. J., Hicks, A. A., …Wisden, W. (1989)
The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies. In Molecular Biology of Neuroreceptors and Ion Channels, 83-99. Springer Verlag. https://doi.org/10.1007/978-3-642-74155-5_7
It is well established that the inhibitory neurotransmitter γ-aminobutyric acid (GABA) mediates many of its effects by binding to the GABAA receptor, which is present on the m...
Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease
Journal Article
Buckle, V. J., Fujita, N., Ryder-Cook, A. S., Derry, J. M., Barnard, P. J., Lebo, R. V., …Barnard, E. A. (1989)
Chromosomal localization of GABAA receptor subunit genes: relationship to human genetic disease. Neuron, 3(5), 647-654. https://doi.org/10.1016/0896-6273%2889%2990275-4
Hybridization of {GABAA} receptor probes to human chromosomes in situ and to {DNA} from sorted human chromosomes has localized the genes encoding a β subunit and three isoform...
The molecular basis of muscular dystrophy in the mdx mouse: a point mutation
Journal Article
Sicinski, P., Geng, Y., Ryder-Cook, A., Barnard, E., Darlison, M., & Barnard, P. (1989)
The molecular basis of muscular dystrophy in the mdx mouse: a point mutation. Science, 244(4912), 1578-1580. https://doi.org/10.1126/science.2662404
The mdx mouse is an X-linked myopathic mutant, an animal model for human Duchenne muscular dystrophy. In both mouse and man the mutations lie within the dystrophin gene, but t...