Oestrogen formation and connective tissue growth factor expression in rat granulosa cells
Journal Article
Harlow, C. R., Bradshaw, A. C., Rae, M. T., Shearer, K. D., & Hillier, S. G. (2007)
Oestrogen formation and connective tissue growth factor expression in rat granulosa cells. Journal of Endocrinology, 192(1), 41-52. https://doi.org/10.1677/joe.1.06689
Ovarian follicular development involves continual remodelling of the extracellular matrix (ECM) forming the basement membrane and intercellular framework that support granulos...
Protein kinase C- and Ca2+ ionophore-stimulated production of reactive oxygen species in mechanically dispersed isolated bovine luteal cells
Journal Article
Sakka, E., Rae, M., Bramley, T., & Aitken, J. (1997)
Protein kinase C- and Ca2+ ionophore-stimulated production of reactive oxygen species in mechanically dispersed isolated bovine luteal cells. Biology of Reproduction, 57(2), 428-435
We measured the production of reactive oxygen species (ROS) using luminol-horseradish peroxidase-induced chemiluminescence in mechanically dispersed cell suspensions from bovi...
Urinary specific gravity as an alternative for the normalisation of endocrine metabolite concentrations in giant panda (Ailuropoda melanoleuca) reproductive monitoring
Journal Article
Wauters, J., Wilson, K. S., Bouts, T., Valentine, I., Vanderschueren, K., Ververs, C., …Vanhaecke, L. (2018)
Urinary specific gravity as an alternative for the normalisation of endocrine metabolite concentrations in giant panda (Ailuropoda melanoleuca) reproductive monitoring. PLOS ONE, 13(7), https://doi.org/10.1371/journal.pone.0201420
Reproductive monitoring for captive breeding in giant pandas is based on behavioural observation and non-invasive hormone analysis. In urine, interpretation of results require...
Steroid signalling in the ovarian surface epithelium
Journal Article
Rae, M. T., & Hillier, S. G. (2005)
Steroid signalling in the ovarian surface epithelium. Trends in Endocrinology and Metabolism, 16(7), 327-333. https://doi.org/10.1016/j.tem.2005.07.002
Human ovarian surface epithelium (HOSE) undergoes serial injury-repair with each ovulation, which is probably why most ovarian epithelial cancers arise there. Considering the ...
Glucocorticoid receptor-mediated regulation of MMP9 gene expression in human ovarian surface epithelial cells
Journal Article
Rae, M. T., Price, D., Harlow, C. R., Critchley, H. O. D., & Hillier, S. G. (2009)
Glucocorticoid receptor-mediated regulation of MMP9 gene expression in human ovarian surface epithelial cells. Fertility and Sterility, 92(2), 703-708. https://doi.org/10.1016/j.fertnstert.2008.06.040
Objective
To obtain proof-of-concept that locally produced anti-inflammatory steroids suppress ovulation-associated extracellular matrix proteases in human ovarian surface epi...