Type 1 diabetes patients with different residual beta-cell function but similar age, HBA1c, and cardiorespiratory fitness have differing exercise-induced angiogenic cell mobilisation
Journal Article
Taylor, G. S., Shaw, A., Scragg, J. H., Smith, K., Campbell, M. D., Mcdonald, T. J., …West, D. J. (2022)
Type 1 diabetes patients with different residual beta-cell function but similar age, HBA1c, and cardiorespiratory fitness have differing exercise-induced angiogenic cell mobilisation. Frontiers in Endocrinology, 13, https://doi.org/10.3389/fendo.2022.797438
Background:
Many individuals with type 1 diabetes retain residual beta-cell function. Sustained endogenous insulin and C-peptide secretion is associated with reduced diabetes ...
Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic
Journal Article
Mclaughlin, M., Florida-James, G., & Ross, M. (2021)
Breast cancer chemotherapy vascular toxicity: A review of mediating mechanisms and exercise as a potential therapeutic. Vascular Biology, 3(1), R106-R120. https://doi.org/10.1530/VB-21-0013
Breast cancer chemotherapy, although very potent against tumour tissue, results in significant cardiovascular toxicity. The focus of research in this area has been predominant...
Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated
Journal Article
Taylor, G. S., Shaw, A., Smith, K., Capper, T. E., Scragg, J. H., Cronin, M., …West, D. J. (2021)
Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated. Scientific Reports, 11, https://doi.org/10.1038/s41598-021-93886-2
Background: Exercise mobilizes angiogenic cells, which stimulate vascular repair. However, limited research suggests exercise-induced increase of endothelial progenitor cell (...
CD34+ progenitors are predictive of mortality and are associated with physical activity in cardiovascular disease patients
Journal Article
Muggeridge, D., Dodd, J., & Ross, M. D. (2021)
CD34+ progenitors are predictive of mortality and are associated with physical activity in cardiovascular disease patients. Atherosclerosis, 333, 108-115. https://doi.org/10.1016/j.atherosclerosis.2021.07.004
Background and aims
Circulating progenitor cells (CPCs) play an important role in vascular repair and can influence cardiovascular (CV) health and longevity. Exercise is known...
Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age
Journal Article
Lithgow, H., Florida‐James, G., Ross, M., Duncan, G., & Leggate, M. (2021)
Exercise acutely increases vitamin D receptor expression in T lymphocytes in vitamin D-deficient men, independent of age. Experimental Physiology, 106(7), 1460-1469. https://doi.org/10.1113/ep089480
Vitamin D plays a key role in the modulation of the immune system, mediated through the intracellular vitamin D receptor (VDR). Exercise has been shown to influence the activi...
The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system
Journal Article
Ellison-Hughes, G. M., Colley, L., O'Brien, K. A., Roberts, K. A., Agbaedeng, T. A., & Ross, M. (2020)
The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system. Frontiers in Cardiovascular Medicine, 7, https://doi.org/10.3389/fcvm.2020.602183
The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19) has led to 47m infected cases and 1.2m (2.6...
Vascular Manifestations of COVID-19 -Thromboembolism and Microvascular Dysfunction
Journal Article
Roberts, K. A., Colley, L., Agbaedeng, T. A., Ellison-Hughes, G. M., & Ross, M. D. (2020)
Vascular Manifestations of COVID-19 -Thromboembolism and Microvascular Dysfunction. Frontiers in Cardiovascular Medicine, 7, https://doi.org/10.3389/fcvm.2020.598400
The coronavirus pandemic has reportedly infected over 22 million individuals and caused over 778,000 deaths worldwide. This novel coronavirus, officially named severe acute re...
The effect of exercise intensity and duration on cardiac troponin release
Journal Article
Mills, N., Marshall, L., Lee, K. K., Stewart, S., Wild, A., Fujisawa, T., …Ross, M. (2020)
The effect of exercise intensity and duration on cardiac troponin release. Circulation, 141(1), 83-85. https://doi.org/10.1161/CIRCULATIONAHA.119.041874
Abstract not available.
Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men.
Journal Article
Montgomery, R., Paterson, A., Williamson, C., Florida-James, G., & Ross, M. D. (2019)
Blood flow restriction exercise attenuates the exercise-induced endothelial progenitor cells in healthy, young men. Frontiers in Physiology, https://doi.org/10.3389/fphys.2019.00447
Endothelial progenitor cells (EPCs) are a vasculogenic subset of progenitors, which play a key role in maintenance of endothelial integrity. These cells are exercise-responsiv...
Circulating angiogenic cell response to sprint interval and continuous exercise.
Journal Article
O'Carroll, L., Wardrop, B., Murphy, R. P., Ross, M. D., & Harrison, M. (2019)
Circulating angiogenic cell response to sprint interval and continuous exercise. European Journal of Applied Physiology, 119(3), 743-752. https://doi.org/10.1007/s00421-018-04065-7
Although commonly understood as immune cells, certain T lymphocyte and monocyte subsets have angiogenic potential, contributing to blood vessel growth and repair. These cells ...