6 results

A perspective on the developmental toxicity of inhaled nanoparticles.

Journal Article
Hougaard, K. S., Campagnolo, L., Chavatte-Palmer, P., Tarrade, A., Rousseau-Ralliard, D., Valentino, S., …Cassee, F. R. (2015)
A perspective on the developmental toxicity of inhaled nanoparticles. Reproductive Toxicology, 56, 118-140. https://doi.org/10.1016/j.reprotox.2015.05.015
This paper aimed to clarify whether maternal inhalation of engineered nanoparticles (NP) may constitute a hazard to pregnancy and fetal development, primarily based on experim...

Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status

Journal Article
Prach, M., Stone, V., & Proudfoot, L. (2012)
Zinc oxide nanoparticles and monocytes: Impact of size, charge and solubility on activation status. Toxicology and Applied Pharmacology, 266(1), 19-26. https://doi.org/10.1016/j.taap.2012.10.020
Zinc oxide (ZnO) particle induced cytotoxicity was dependent on size, charge and solubility, factors which at sublethal concentrations may influence the activation of the huma...

Evaluating the uptake, intracellular fate and functional consequences of hepatocyte exposure to a range of nanoparticles, in vitro

Thesis
Johnston, H. Evaluating the uptake, intracellular fate and functional consequences of hepatocyte exposure to a range of nanoparticles, in vitro. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/2548
The liver is recognised as a potential target site for nanoparticle (NP) toxicity, as NPs have been observed to accumulate within this organ subsequent to exposure via injecti...

Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation

Journal Article
Wilson, M. R., Foucaud, L., Barlow, P. G., Hutchison, G. R., Sales, J., Simpson, R. J., & Stone, V. (2007)
Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation. Toxicology and Applied Pharmacology, 225(1), 80-89. https://doi.org/10.1016/j.taap.2007.07.012
Particulate air pollution (PM10) consists of a mixture of components, including nanoparticles and metals. Studies from our laboratory have demonstrated that transition metals ...

Multi-walled carbon nanotube induced frustrated phagocytosis, cytotoxicity and pro-inflammatory conditions in macrophages are length dependent and greater than that of asbestos

Journal Article
Boyles, M. S., Young, L., Brown, D. M., MacCalman, L., Cowie, H., Moisala, A., …Stone, V. (2015)
Multi-walled carbon nanotube induced frustrated phagocytosis, cytotoxicity and pro-inflammatory conditions in macrophages are length dependent and greater than that of asbestos. Toxicology in Vitro, 29(7), 1513-1528. https://doi.org/10.1016/j.tiv.2015.06.012
The potential toxicity of carbon nanotubes (CNTs) has been compared to pathogenic fibres such as asbestos. It is important to test this hypothesis to ascertain safe methods fo...

Molecular toxicology studies on the quartz hazard.

Thesis
Duffin, R. Molecular toxicology studies on the quartz hazard. (Thesis)
Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/2777
Silicon makes up almost 28% of the Earth's crust and within that crust, quartz (crystalline silica) is one of the most abundant minerals. Exposure to quartz can occur in a num...

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