42 results

TNF-α induced DNA damage in primary murine hepatocytes

Journal Article
Chan, Y., Gillies, S., Ross, J., Harrison, D., Wheelhouse, N., Chan, Y., …Prost, S. (2003)
TNF-α induced DNA damage in primary murine hepatocytes. International Journal of Molecular Medicine, 12(6), (889-894). doi:10.3892/ijmm.12.6.889. ISSN 1107-3756
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, usually arising from a background of chronic inflammatory disease. Tumor necrosis factor alpha (TNF...

Analysis of the elements of catabolite repression in Clostridium acetobutylicum.

Journal Article
Tangney, M., Deutscher, J., Galinier, A. & Mitchell, W. J. (2003)
Analysis of the elements of catabolite repression in Clostridium acetobutylicum. Journal of Molecular Microbiology and Biotechnology. 6, 6-11. doi:10.1159/000073403. ISSN 1464-1801
The ptsH gene, encoding the phosphotransferase protein HPr, from Clostridium acetobutylicum ATCC 824 was identified from the genome sequence, cloned and shown to complement a ...

Cellular responses of developing Fucus serratus embryos exposed to elevated concentrations of Cu2+.

Journal Article
Nielsen, H. D., Brown, M. T., & Brownlee, C. (2003)
Cellular responses of developing Fucus serratus embryos exposed to elevated concentrations of Cu2+. Plant, Cell and Environment, 26(10), (1737-1747). doi:10.1046/j.1365-3040.2003.01091.x. ISSN 0140-7791
Elevated concentrations of Cu2+ can have inhibitory effects on early development in plants and algae by targeting specific cellular processes. In the present study the effects...

DNA-Binding Activity of the Streptococcus thermophilus Phage Sfi21 Repressor

Journal Article
Bruttin, A., Foley, S., & Brüssow, H. (2002)
DNA-Binding Activity of the Streptococcus thermophilus Phage Sfi21 Repressor. Virology, 303(1), 100-109. doi:10.1006/viro.2002.1574
The cloned Streptococcus thermophilus phage Sfi21 repressor open reading frame (orf) 127 gp protects a cell against superinfection with the homologous temperate, but not again...

Lactobacillus helveticus ATCC15009 as a host for native and conjugative plasmid DNA.

Book
Thompson, K., Collins, M. A., & Foley, S. (2002)
Lactobacillus helveticus ATCC15009 as a host for native and conjugative plasmid DNA. In S. G. Pandalai (Ed.), Recent Research Developments in Plasmid Biology, 55-74. Research Signpost/Transworld Research Network
The plasmid complement of Lactobacillus helveticus ATCC15009 (plasmids pLH1, pLH2 and pLH3) has been sequenced and is being analysed for functional properties. Sequences used ...

Transcription Mapping as a Tool in Phage Genomics: The Case of the Temperate Streptococcus thermophilus Phage Sfi21

Journal Article
Ventura, M., Foley, S., Bruttin, A., Chennoufi, S. C., Canchaya, C., & Brüssow, H. (2002)
Transcription Mapping as a Tool in Phage Genomics: The Case of the Temperate Streptococcus thermophilus Phage Sfi21. Virology, 296(1), 62-76. doi:10.1006/viro.2001.1331
For the lytic growth cycle of the temperate cos-site Streptococcus thermophilus phage Sfi21 a transcription map was developed on the basis of systematic Northern blot hybridiz...

Genomics, molecular genetics and the food industry

Journal Article
Pridmore, R., Crouzillat, D., Walker, C., Foley, S., Zink, R., Zwahlen, M., …Mollet, B. (2000)
Genomics, molecular genetics and the food industry. Journal of Biotechnology, 78(3), 251-258. https://doi.org/10.1016/s0168-1656%2800%2900202-9
The production of foods for an increasingly informed and selective consumer requires the coordinated activities of the various branches of the food chain in order to provide c...

Molecular Analysis of the Replication Origin of the Lactococcus lactis Plasmid pCI305

Journal Article
Foley, S., Bron, S., Venema, G., Daly, C., & Fitzgerald, G. F. (1996)
Molecular Analysis of the Replication Origin of the Lactococcus lactis Plasmid pCI305. Plasmid, 36(2), 125-141. https://doi.org/10.1006/plas.1996.0040
The replication origin region, ori, of the Lactococcus lactis subsp. lactis plasmid pCI305 contains three-and-one-half directly repeated 22-bp sequences and two inverted repea...

Alternative Splicing of a 51-Nucleotide Exon that Encodes a Putative Protein Kinase C Phosphorylation Site Generates Two Forms of the Chicken γ-Aminobutyric AcidAReceptor β2 Subunit

Journal Article
Harvey, R. J., Chinchetru, M. A., & Darlison, M. G. (1994)
Alternative Splicing of a 51-Nucleotide Exon that Encodes a Putative Protein Kinase C Phosphorylation Site Generates Two Forms of the Chicken γ-Aminobutyric AcidAReceptor β2 Subunit. Journal of Neurochemistry, 62(1), 10-16. https://doi.org/10.1046/j.1471-4159.1994.62010010.x
Complementary DNAs that encode two forms of the chicken -γ-aminobutyric acid type A (GABAA) receptor β2 subunit have been isolated. These polypeptides differ by the presence (...

Molecular cloning reveals the existence of a fourth γ subunit of the vertebrate brain GABAAreceptor

Journal Article
Harvey, R. J., Kim, H., & Darlison, M. G. (1993)
Molecular cloning reveals the existence of a fourth γ subunit of the vertebrate brain GABAAreceptor. FEBS Letters, 331(3), 211-216. https://doi.org/10.1016/0014-5793%2893%2980339-v
We have isolated a cDNA, from the chicken, that encodes a fourth type of γ subunit of the vertebrate brain GABAA receptor. The mature polypeptide (which we name γ4) displays 6...

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