The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein.
Journal Article
Johnson, D. A. & Smith, K. (2006)
The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein. Biomedical Chromatography. 20, 551-560. doi:10.1002/bmc.641. ISSN 0269-3879
One of the most ubiquitous plasma proteins, -1-acid glycoprotein (AGP), has a high affinity, low capacity binding for basic drugs positively charged at physiological pH. Moreo...