3 results

Role of androgens in fetal testis development and dysgenesis.

Journal Article
Scott, H. M., Hutchison, G. R., Mahood, I. K., Hallmark, N., Welsh, M., De Gendt, K., …Sharpe, R. M. (2007)
Role of androgens in fetal testis development and dysgenesis. Endocrinology. 148, 2027-2036. doi:10.1210/en.2006-1622. ISSN 0013-7227
This study sought to establish whether reduced androgen levels/action in the fetal rat testis induced by di(n-butyl) phthalate (DBP) contributes to dysgenetic features, namely...

Thyroid hormone signaling in human ovarian surface epithelial cells.

Journal Article
Rae, M. T., Gubbay, O., NaKostogiannou, A., Price, D., Critchley, H. O. D. & Hillier, S. G. (2007)
Thyroid hormone signaling in human ovarian surface epithelial cells. Journal of Clinical Endocrinology and Metabolism. 92, 322-327. doi:10.1210/jc.2006-1522. ISSN 0021-972X
Ovarian surface epithelial (OSE) cells express multiple nuclear hormone receptor genes, including those encoding thyroid hormone and estrogen receptors (TR and ER, respectivel...

The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein.

Journal Article
Johnson, D. A. & Smith, K. (2006)
The efficacy of certain anti-tuberculosis drugs is affected by binding to alpha-1-acid glycoprotein. Biomedical Chromatography. 20, 551-560. doi:10.1002/bmc.641. ISSN 0269-3879
One of the most ubiquitous plasma proteins, -1-acid glycoprotein (AGP), has a high affinity, low capacity binding for basic drugs positively charged at physiological pH. Moreo...