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Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential

Journal Article
Sharma, A., Goring, A., Staines, K., Emery, R., Pitsillides, A. A., Oreffo, R. O., …Clarkin, C. E. (2020)
Raman spectroscopy links differentiating osteoblast matrix signatures to pro-angiogenic potential. Matrix Biology Plus, 5, https://doi.org/10.1016/j.mbplus.2019.100018
Mineralization of bone is achieved by the sequential maturation of the immature amorphous calcium phase to mature hydroxyapatite and is central to the process of bone developm...

The Effects of morpholine pre-treated and carboxymethylated cellulose nanofibrils on the properties of alginate-based hydrogels

Journal Article
Onyianta, A. J., Castellano, M., Dorris, M., Williams, R. L., & Vicini, S. (2018)
The Effects of morpholine pre-treated and carboxymethylated cellulose nanofibrils on the properties of alginate-based hydrogels. Carbohydrate Polymers, 198, 320-327. https://doi.org/10.1016/j.carbpol.2018.06.084
The effects of varying percentage loadings of morpholine pre-treated cellulose nanofibrils (MCNF) and carboxymethylated cellulose nanofibrils (CMCNF) on the aqueous swelling, ...

A computational analysis of methanol autoignition enhancement by dimethyl ether addition in a counterflow mixing layer

Journal Article
Song, W., Tingas, E., & Im, H. G. (2018)
A computational analysis of methanol autoignition enhancement by dimethyl ether addition in a counterflow mixing layer. Combustion and Flame, 195, 84-98. https://doi.org/10.1016/j.combustflame.2018.03.037
To provide fundamental insights into the ignition enhancement of methanol (MeOH) by the addition of the more reactive dimethyl ether (DME), computational parametric studies we...

Disastrous performance of NanoCote/Aqua Based antimicrobial paint in a hospital setting

Journal Article
Ramsden, J., Reid, M., Whatley, V., & Dancer, S. (2016)
Disastrous performance of NanoCote/Aqua Based antimicrobial paint in a hospital setting. Journal of Biological Physics and Chemistry, 16(3), 131-136. https://doi.org/10.4024/16ra16a.jbpc.16.03
Attempts are being made to incorporate copper into clear varnish in order to coat environmental surfaces in hospitals with the long-term goal of reducing healthcare-acquired i...

Aqueous solutions of HEC and hmHEC: effects of molecular mass versus hydrophobic associations on hydrodynamic and thermodynamic parameters.

Journal Article
Vadodaria, S. S., & English, R. J. (2016)
Aqueous solutions of HEC and hmHEC: effects of molecular mass versus hydrophobic associations on hydrodynamic and thermodynamic parameters. Cellulose, 23(2), 1107-1121. https://doi.org/10.1007/s10570-016-0861-x
Aqueous solutions of amphiphilic polymers usually comprise of inter- and intramolecular associations of hydrophobic groups often leading to a formation of a rheologically sign...

Extensional rheometry of cellulose ether solutions: flow instability

Journal Article
Vadodaria, S. S., & English, R. J. (2015)
Extensional rheometry of cellulose ether solutions: flow instability. Cellulose, 23(1), 339-355. https://doi.org/10.1007/s10570-015-0838-1
Capillary breakup extensional rheometry of semi-dilute hydroxyethyl cellulose (HEC) solutions was performed under several step-stretch conditions. The resulting parameters, i....

Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression

Journal Article
Gordon, K., Clouaire, T., Bao, X. X., Kemp, S. E., Xenophontos, M., de Las Heras, J. I., & Stancheva, I. (2014)
Immortality, but not oncogenic transformation, of primary human cells leads to epigenetic reprogramming of DNA methylation and gene expression. Nucleic Acids Research, 42(6), 3529-3541. https://doi.org/10.1093/nar/gkt1351
Tumourigenic transformation of normal cells into cancer typically involves several steps resulting in acquisition of unlimited growth potential, evasion of apoptosis and non-r...

A ferrocene nucleic acid oligomer as an organometallic structural mimic of DNA

Journal Article
Nguyen, H. V., Zhao, Z., Sallustrau, A., Horswell, S. L., Male, L., Mulas, A., & Tucker, J. H. R. (2012)
A ferrocene nucleic acid oligomer as an organometallic structural mimic of DNA. Chemical Communications, 48, 12165. https://doi.org/10.1039/C2CC36428J
The design, synthesis and electrochemical behaviour of an oligomer consisting of linked thymine-functionalised ferrocene units are reported, which, as a so-called form of ferr...

Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe

Journal Article
Zhao, Z., San, M., Duprey, J. H. A., Arrand, J. R., Vyle, J. S., & Tucker, J. H. R. (2012)
Detection of single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer using a fluorophore-tagged DNA probe. Bioorganic and Medicinal Chemistry Letters, 22(1), 129-132. https://doi.org/10.1016/j.bmcl.2011.11.053
Single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer were identified using oligodeoxynucleotide probe sequences bearing internal anthrac...

Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe

Journal Article
Duprey, J. H. A., Zhao, Z., Bassani, D. M., Manchester, J., Vyle, J. S., & Tucker, J. H. R. (2011)
Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe. Chemical Communications, 47, 6629. https://doi.org/10.1039/c1cc11205h
A fluorescent DNA probe containing an anthracene group attached via an anucleosidic linker can identify all four DNA bases at a single site as well as the epigenetic modificat...