Genetic linkage and radiation hybrid mapping of the three human GABAC receptor ρ subunit genes: GABRR1, GABRR2 and GABRR3
Journal Article
Bailey, M. E., Albrecht, B. E., Johnson, K. J., & Darlison, M. G. (1999)
Genetic linkage and radiation hybrid mapping of the three human GABAC receptor ρ subunit genes: GABRR1, GABRR2 and GABRR3. BBA - Gene Structure and Expression, 1447(2-3), 307-312. https://doi.org/10.1016/s0167-4781%2899%2900167-0
{GABAC} receptors mediate rapid inhibitory neurotransmission in retina. We have mapped, in detail, the human genes which encode the three polypeptides that comprise this recep...
Genomic mapping and evolution of human GABAA receptor subunit gene clusters
Journal Article
Bailey, M. E. S., Matthews, D. A., Riley, B. P., Albrecht, B. E., Kostrzewa, M., Hicks, A. A., …Johnson, K. J. (1999)
Genomic mapping and evolution of human GABAA receptor subunit gene clusters. Mammalian Genome, 10(8), 839-843. https://doi.org/10.1007/s003359901101
No abstract available.
Multiple genes for neuropeptides and their receptors: co-evolution and physiology
Journal Article
Darlison, M. G., & Richter, D. (1999)
Multiple genes for neuropeptides and their receptors: co-evolution and physiology. Trends in Neurosciences, 22(2), 81-88. https://doi.org/10.1016/S0166-2236%2898%2901333-2
It is now well established that neuropeptide receptors, which are present throughout the {CNS} and in peripheral tissues, frequently exist in a variety of different forms (cal...
Expression of the GABAA receptor gamma4-subunit gene: anatomical distribution of the corresponding mRNA in the domestic chick forebrain and the effect of imprinting training
Journal Article
Harvey, R. J., McCabe, B. J., Solomonia, R. O., Horn, G., & Darlison, M. G. (1998)
Expression of the GABAA receptor gamma4-subunit gene: anatomical distribution of the corresponding mRNA in the domestic chick forebrain and the effect of imprinting training. The European journal of neuroscience, 10(9), 3024-3028. https://doi.org/10.1046/j.1460-9568.1998.00354.x
The learning process of imprinting involves morphological, electrophysiological and biochemical changes in a region of the chick (Gallus gallus domesticus) forebrain known as ...
Chicken GABAA receptor β4 subunits form robust homomeric GABA-gated channels in Xenopus oocytes
Journal Article
Liu, S., Parent, L., Harvey, R. J., Darlison, M. G., & Eugene, J. M. B. (1998)
Chicken GABAA receptor β4 subunits form robust homomeric GABA-gated channels in Xenopus oocytes. European Journal of Pharmacology, 354(2-3), 253-259. https://doi.org/10.1016/S0014-2999%2898%2900453-1
Chicken {GABAA} receptor β4L and β4S subunits were expressed in Xenopus oocytes by cRNA injection. Oocytes expressing either β4 subunit alone or in combination with the chicke...
Reliable and accurate sequencing of lambda, cosmid and P1 DNAs using modified dye terminator reaction parameters
Journal Article
Harvey, R. J., Harder, S., & Darlison, M. G. (1998)
Reliable and accurate sequencing of lambda, cosmid and P1 DNAs using modified dye terminator reaction parameters. Technical tips online, 3(1), 150-152. https://doi.org/10.1016/S1366-2120%2808%2970126-0
Many laboratories still find the direct sequencing of large DNA templates (i.e. lambda, cosmid and bacteriophage P1 clones) problematic. To date, only limited amounts of seque...
In Situ Hybridization and Reverse Transcription-Polymerase Chain Reaction Studies on the Expression of the GABAc Receptor ρ1- and ρ2-subunit Genes in Avian and Rat Brain
Journal Article
Albrecht, B. E., Breitenbach, U., Stühmer, T., Harvey, R. J., & Darlison, M. G. (1997)
In Situ Hybridization and Reverse Transcription-Polymerase Chain Reaction Studies on the Expression of the GABAc Receptor ρ1- and ρ2-subunit Genes in Avian and Rat Brain. European Journal of Neuroscience, 9(11), 2414-2422. https://doi.org/10.1111/j.1460-9568.1997.tb01658.x
The pharmacological properties of homo-oligomeric channels formed by the GABA type A receptor-like ρl and ρ2 polypeptides are very reminiscent of those of the GABA type C rece...
Candidate gene study of eight GABAA receptor subunits in panic disorder
Journal Article
Darlison, M. G., Bailey, M., Johnson, K., Wang, Z., Crowe, R., Albrecht, B., …Zoega, T. (1997)
Candidate gene study of eight GABAA receptor subunits in panic disorder. American Journal of Psychiatry, 154(8), 1096-1100. https://doi.org/10.1176/ajp.154.8.1096
OBJECTIVE: gamma-Aminobutyric acid type A (GABAA) receptor subunit genes are candidate genes for panic disorder. Benzodiazepine agonists acting at this receptor can suppress p...
Opioid receptors from a lower vertebrate (Catostomus commersoni): Sequence, pharmacology, coupling to a G-protein-gated inward-rectifying potassium channel (GIRK1), and evolution
Journal Article
Darlison, M. G., Greten, F. R., Harvey, R. J., Kreienkamp, H., Stühmer, T., Zwiers, H., …Richter, D. (1997)
Opioid receptors from a lower vertebrate (Catostomus commersoni): Sequence, pharmacology, coupling to a G-protein-gated inward-rectifying potassium channel (GIRK1), and evolution. Proceedings of the National Academy of Sciences, 94(15), 8214-8219
The molecular evolution of the opioid receptor family has been studied by isolating cDNAs that encode six distinct opioid receptor-like proteins from a lower vertebrate, the t...
In Situ Hybridization Localization of the GABAA Receptor β2S- and β2L-Subunit Transcripts Reveals Cell-Specific Splicing of Alternate Cassette Exons
Journal Article
Harvey, R., & Darlison, M. (1997)
In Situ Hybridization Localization of the GABAA Receptor β2S- and β2L-Subunit Transcripts Reveals Cell-Specific Splicing of Alternate Cassette Exons. Neuroscience, 77(2), 361-369. https://doi.org/10.1016/S0306-4522%2896%2900467-8
We have recently described two variants of the chicken {GABAA} receptor β2 subunit which arise by alternative splicing of the corresponding primary gene transcript. The long f...