3 results

Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo.

Journal Article
Taylor, M. D., LeGoff, L., Harris, A., Malone, E. M., Allen, J. E., & Maizels, R. M. (2005)
Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. Journal of Immunology, 174, 4924-4933
Human filarial parasites cause chronic infection associated with long-term down-regulation of the host’s immune response. We show here that CD4+ T cell regulation is the main ...

Nanotoxicity.

Book Chapter
Hutchison, G. R., & Malone, E. M. (2011)
Nanotoxicity. In B. Booß-Bavnbek, B. Klösgen, J. Larsen, F. Pociot, & E. Renström (Eds.), Systems Biology of Regulated Exocytosis in Pancreatic β-Cells, 419-434. Springer. https://doi.org/10.1007/978-1-4419-6956-9_18
Nanotechnology, including the field of nanomedicine, promises to revolutionise/improve the way in which we live our lives. This atomic, molecular and macromolecular technology...

The influence of age and cardiorespiratory fitness on circulating angiogenic T cells and CXCR4 expression.

Conference Proceeding
Ross, M. D., Malone, E. M., Simpson, R. J., & Florida-James, G. (2015)
The influence of age and cardiorespiratory fitness on circulating angiogenic T cells and CXCR4 expression
Aging is associated with endothelial dysfunction, reduced angiogenic capabilities, and an increase in arterial stiffness. Additionally, regular exercise is known to offset the...