Research Output
In a large primary care dataset, the CHA₂DS₂-VASc score leads to almost universal recommendation for anticoagulation treatment in those aged ≥65 years with atrial fibrillation
  From 2012-16, the oral anticoagulant (OAC) treatment determination for atrial fibrillation (AF) patients moved from the CHADS₂ to the CHA₂DS₂-VASc score. A dataset collated during previous studies (2011-2019) with deidentified data extracted from clinical records at a single-timepoint for active adult patients (n=285,635; 8,294 with AF) attending 164 general practices in Australia was analysed. The CHA₂DS₂-VASc threshold (score ≥2 men/≥3 women) captured a significantly higher proportion than CHADS₂≥2 (all ages: 85% vs 68%, p<0.0001; ≥65 years: 96% vs 76%, p<0.0001). The change from CHADS₂ to CHA₂DS₂-VASc resulted in a significantly higher proportion of AF patients being recommended OAC, driven by the revised scoring for age.

  • Type:

    Article

  • Date:

    03 January 2023

  • Publication Status:

    In Press

  • Publisher

    Oxford University Press (OUP)

  • DOI:

    10.1093/eurjcn/zvad002

  • Cross Ref:

    10.1093/eurjcn/zvad002

  • ISSN:

    1474-5151

  • Funders:

    New Funder

Citation

Orchard, J. J., Giskes, K., Orchard, J. W., La Gerche, A., Neubeck, L., Hespe, C., …Freedman, B. (in press). In a large primary care dataset, the CHA₂DS₂-VASc score leads to almost universal recommendation for anticoagulation treatment in those aged ≥65 years with atrial fibrillation. European Journal of Cardiovascular Nursing, https://doi.org/10.1093/eurjcn/zvad002

Authors

Keywords

stroke prevention, general practice, atrial fibrillation

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