The molecular basis of muscular dystrophy in the mdx mouse: a point mutation
Journal Article
Sicinski, P., Geng, Y., Ryder-Cook, A., Barnard, E., Darlison, M., & Barnard, P. (1989)
The molecular basis of muscular dystrophy in the mdx mouse: a point mutation. Science, 244(4912), 1578-1580. https://doi.org/10.1126/science.2662404
The mdx mouse is an X-linked myopathic mutant, an animal model for human Duchenne muscular dystrophy. In both mouse and man the mutations lie within the dystrophin gene, but t...
Differential distribution in bovine brain of distinct γ-aminobutyric acid A receptor α-subunit mRNAs
Journal Article
WISDEN, W., MORRIS, B. J., DARLISON, M. G., HUNT, S. P., & BARNARD, E. A. (1989)
Differential distribution in bovine brain of distinct γ-aminobutyric acid A receptor α-subunit mRNAs. Transactions, 17(3), 566-567. https://doi.org/10.1042/bst0170566
No abstract available.
Distinct GABAA receptor α subunit mRNAs show differential patterns of expression in bovine brain
Journal Article
Wisden, W., Morris, B. J., Darlison, M. G., Hunt, S. P., & Barnard, E. A. (1988)
Distinct GABAA receptor α subunit mRNAs show differential patterns of expression in bovine brain. Neuron, 1(10), 937-947. https://doi.org/10.1016/0896-6273%2888%2990151-1
Specific oligonucleotide probes have been used to visualize the regional and cellular distribution of the mRNAs encoding three structurally distinct GABA A receptor α subunits...
Structural and functional basis for GABAA receptor heterogeneity
Journal Article
Levitan, E. S., Schofield, P. R., Burt, D. R., Rhee, L. M., Wisden, W., Köhler, M., …Seeburg, P. H. (1988)
Structural and functional basis for GABAA receptor heterogeneity. Nature, 335(6185), 76-79. https://doi.org/10.1038/335076a0
When γ-aminobutyric acid (GABA), the major inhibitory neurotransmitter in vertebrate brain, binds to its receptor it activates a chloride channel. Neurotransmitter action at t...