The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy
Biskou, O., Casanova, V., Hooper, K., Kemp, S., Wright, G. P., Satsangi, J., …Stevens, C. (2019)
The type III intermediate filament vimentin regulates organelle distribution and modulates autophagy. PLOS ONE, 14(1), https://doi.org/10.1371/journal.pone.0209665
The cytoskeletal protein vimentin plays a key role in positioning of organelles within the cytosol and has been linked to the regulation of numerous cellular processes includi...
Immunological homeostasis at the ovine placenta may reflect the degree of maternal foetal interaction
Wattegedera, S. R., Doull, L. E., Goncheva, M. I., Wheelhouse, N., Watson, D. M., Pearce, J., …Entrican, G. (2019)
Immunological homeostasis at the ovine placenta may reflect the degree of maternal foetal interaction. Frontiers in Immunology, 9, https://doi.org/10.3389/fimmu.2018.03025
Successful mammalian pregnancies are a result of complex physiological, endocrinological and immunological processes that combine to create an environment where the mother is ...
Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry
Dancer, S. J., & Kramer, A. (2019)
Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry. Journal of Hospital Infection, 103(1), e1-e8. https://doi.org/10.1016/j.jhin.2018.12.015
Now that cleaning and decontamination are recognised as integral to infection control, it is timely to examine the process in more detail. This is because cleaning ...
Shining a light on ultraviolet-C disinfection: No golden promises for infection prevention
de Kraker, M. E. A., Harbarth, S., & Dancer, S. J. (2018)
Shining a light on ultraviolet-C disinfection: No golden promises for infection prevention. American Journal of Infection Control, 46(12), 1422-1423. doi:10.1016/j.ajic.2018.07.026
No abstract available.
Antiviral therapeutic approaches for human rhinovirus infections
Casanova, V., Sousa, F. H., Stevens, C., & Barlow, P. G. (2018)
Antiviral therapeutic approaches for human rhinovirus infections. Future Virology, https://doi.org/10.2217/fvl-2018-0016
Human rhinoviruses (RV) are the primary etiological agent of the common cold. This infection can be mild and self-limiting in immunocompetent hosts, but can be associated wit...
Carbon Nanoparticles Inhibit the Antimicrobial Activities of the Human Cathelicidin LL-37 through Structural Alteration
Findlay, F., Pohl, J., Svoboda, P., Shakamuri, P., McLean, K., Inglis, N. F., …Barlow, P. G. (2017)
Carbon Nanoparticles Inhibit the Antimicrobial Activities of the Human Cathelicidin LL-37 through Structural Alteration. Journal of Immunology, 199(7), 2483-2490. https://doi.org/10.4049/jimmunol.1700706
Host defense peptides, also known as antimicrobial peptides, are key elements of innate host defense. One host defense peptide with well-characterized antimicrobial activity i...
Cathelicidins display conserved direct antiviral activity towards rhinovirus.
Sousa, F. H., Casanova, V., Findlay, F., Stevens, C., Svoboda, P., Pohl, J., …Barlow, P. G. (2017)
Cathelicidins display conserved direct antiviral activity towards rhinovirus. Peptides, 95, 76-83. https://doi.org/10.1016/j.peptides.2017.07.013
Human rhinoviruses (HRVs) are the most common cause of viral respiratory tract infections, and are associated with significant morbidity and mortality in immunocompromised ind...
Antibiotic prescribing: the consequences of getting it wrong
Dancer, S. J. (2016)
Antibiotic prescribing: the consequences of getting it wrong. Clinical Focus Primary Care, 10(2), 62-71
Antibiotics were one of the most important discoveries last century. As with all drugs, however, they are associated with adverse effects. This article reviews how inappropria...
Waddlia chondrophila Infects and Multiplies in Ovine Trophoblast Cells Stimulating an Inflammatory Immune Response
Wheelhouse, N., Coyle, C., Barlow, P. G., Mitchell, S., Greub, G., Baszler, T., …Longbottom, D. (2014)
Waddlia chondrophila Infects and Multiplies in Ovine Trophoblast Cells Stimulating an Inflammatory Immune Response. PLOS ONE, 9(7), https://doi.org/10.1371/journal.pone.0102386
Waddlia chondrophila (W. chondrophila) is an emerging abortifacient organism which has been identified in the placentae of humans and cattle. The organism is a mem...
Antiviral potential of cathelicidins
Barlow, P. G., Findlay, E. G., Currie, S. M., & Davidson, D. J. (2014)
Antiviral potential of cathelicidins. Future Microbiology, 9(1), 55-73. https://doi.org/10.2217/fmb.13.135
The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow. As our understanding of i...