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73 results

Efficacy of two Chlamydia abortus subcellular vaccines in a pregnant ewe challenge model for ovine enzootic abortion

Journal Article
Livingstone, M., Ranjan Wattegedera, S., Palarea-Albaladejo, J., Aitchison, K., Corbett, C., Sait, M., …Longbottom, D. (2021)
Efficacy of two Chlamydia abortus subcellular vaccines in a pregnant ewe challenge model for ovine enzootic abortion. Vaccines, 9(8), Article 898. https://doi.org/10.3390/vaccines9080898
Chlamydia abortus, the aetiological agent of enzootic abortion of ewes, is a major cause of reproductive loss in small ruminants worldwide, accounting for significant economic...

Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated

Journal Article
Taylor, G. S., Shaw, A., Smith, K., Capper, T. E., Scragg, J. H., Cronin, M., …West, D. J. (2021)
Type 1 diabetes patients increase CXCR4+ and CXCR7+ haematopoietic and endothelial progenitor cells with exercise, but the response is attenuated. Scientific Reports, 11, https://doi.org/10.1038/s41598-021-93886-2
Background: Exercise mobilizes angiogenic cells, which stimulate vascular repair. However, limited research suggests exercise-induced increase of endothelial progenitor cell (...

A paradigm shift to combat indoor respiratory infection

Journal Article
Morawska, L., Allen, J., Bahnfleth, W., Bluyssen, P. M., Boerstra, A., Buonanno, G., …Yao, M. (2021)
A paradigm shift to combat indoor respiratory infection. Science, 372(6543), 689-691. https://doi.org/10.1126/science.abg2025
There is great disparity in the way we think about and address different sources of environmental infection. Governments have for decades promulgated a large amount of legisla...

Measurement of the Intracellular Mycobacterium tuberculosis Drug Effect and Prediction of the Clinical Dose–Response Relationship Using Intracellular Pharmacodynamic Modeling (PDi)

Book Chapter
Donnellan, S., Martínez-Rodríguez, C., Aljayyoussi, G., & Biagini, G. A. (2021)
Measurement of the Intracellular Mycobacterium tuberculosis Drug Effect and Prediction of the Clinical Dose–Response Relationship Using Intracellular Pharmacodynamic Modeling (PDi). In C. Barreiro, & J. Barredo (Eds.), Antimicrobial Therapies: Methods and Protocols (393-408). New York: Humana Press. https://doi.org/10.1007/978-1-0716-1358-0
The human disease tuberculosis (TB) is the leading cause of death from a single infectious agent. A quarter of the world’s population is estimated to be latently infected. Dru...

Can we do better? A guide to pandemics – some Dos and Don'ts for the next one

Journal Article
Tang, J. W., Kwok, K. O., Loh, T. P., Lee, C. K., Heraud, J., & Dancer, S. J. (2021)
Can we do better? A guide to pandemics – some Dos and Don'ts for the next one. Journal of Infection, 83(1), 119-145. https://doi.org/10.1016/j.jinf.2021.04.017
Specific features of any rapidly spread pathogen needs early recognition and assessment for possible pandemic potential. These include: inter-person transmissibility and expon...

How dirty is your QWERTY? The risk of healthcare pathogen transmission from computer keyboards

Journal Article
Ledwoch, K., Dancer, S., Otter, J., Kerr, K., Roposte, D., & Maillard, J. (2021)
How dirty is your QWERTY? The risk of healthcare pathogen transmission from computer keyboards. Journal of Hospital Infection, 112, 31-36. https://doi.org/10.1016/j.jhin.2021.02.021
Introduction Healthcare environmental surfaces may be contaminated with micro-organisms that cause healthcare-associated infections (HCAIs). Special attention is paid to near-...

Risk Factors for Leg Ulceration in People Who Inject Drugs: A Cross-Sectional Study

Journal Article
Coull, A. F., Kyle, R. G., Hanson, C. L., & Watterson, A. (2021)
Risk Factors for Leg Ulceration in People Who Inject Drugs: A Cross-Sectional Study. Journal of Clinical Nursing, 30(11-12), 1623-1632. https://doi.org/10.1111/jocn.15716
Aims and Objectives The aim of this study was to assess, for the first time in a hard-to-reach population, the risk factors for leg ulceration among PWID, with the objective o...

Putting a balance on the aerosolization debate around SARS-CoV-2

Journal Article
Dancer, S. J., Tang, J. W., Marr, L. C., Miller, S., Morawska, L., & Jimenez, J. L. (2020)
Putting a balance on the aerosolization debate around SARS-CoV-2. Journal of Hospital Infection, 105(3), 569-570. https://doi.org/10.1016/j.jhin.2020.05.014
No abstract available.

Bacterial Transfer To Fingertips During Sequential Surface Contacts With And Without Gloves

Journal Article
King, M., López‐García, M., Atedoghu, K. P., Zhang, N., Wilson, A. M., Weterings, M., …Fletcher, L. A. (2020)
Bacterial Transfer To Fingertips During Sequential Surface Contacts With And Without Gloves. Indoor Air, 30(5), 993-1004. https://doi.org/10.1111/ina.12682
Bacterial transmission from contaminated surfaces via hand contact plays a critical role in disease spread. However, the fomite‐to‐finger transfer efficiency of microorganisms...

Reducing hand recontamination of healthcare workers during COVID-19

Journal Article
Gon, G., Dancer, S., Dreibelbis, R., Graham, W. J., & Kilpatrick, C. (2020)
Reducing hand recontamination of healthcare workers during COVID-19. Infection Control and Hospital Epidemiology, 41(7), 870-871. https://doi.org/10.1017/ice.2020.111
No abstract available.

Date


31 results

Cathelicidins as Novel Therapeutic Antivirals for Dengue Infection

2019 - 2022
A significant challenge faced by modern society is the lack of therapeutics for a large number of infections, particularly those that are endemic or widely spread in developing countries. Dengue is on...
Funder: Medical Research Council | Value: £269,873

The influence of aerobic exercise training to attenuate chemotherapy-induced cardiotoxicity and vascular dysfunction in breast cancer and leukaemia patients

2018 - 2021
This project will be based in the Sport, Exercise and Health Research theme within the School of Applied Sciences, and is led by Dr. Mark Ross, Miss Karen Campbell and Professor Geraint Florida-James ...
Funder: ENU Development Trust | Value: £58,079

Bacteriophage endolysins and novel lipid-degrading proteins as a treatment for Rhodococcus equi infections in foals

2018 - 2019
Rhodococcus equi (Req) is responsible for severe respiratory disease of foals with a major economic impact on the equine industry, and can be endemic on stud farms. In foals under 6 months of age, thi...
Funder: Horserace Betting Levy Board | Value: £10,832

Rutherford fund Strategic Partner Grant

2018 - 2019
Rutherford Fellows, will work in project areas related to food safety (Pathogen detection, AMR etc) and food spoilage. Rutherford Fund, are funded by BEIS and the scheme is being managed by Universit...
Funder: Department for Business, Energy & Industrial Strategy | Value: £39,800

Ranking novel immune-modulating therapeutics for progression to clinical development

2018 - 2019
Ranking novel immune-modulating therapeutics for progression to clinical development
Funder: Scottish Funding Council | Value: £4,987

Direct and paracrine effects of Chlamydia infection on decidualisation of endometrial stromal cells

2018 - 2018
SRF summer studentship
Funder: Society for Reproduction and Fertility | Value: £2,750

TRANSFORM - Education reform project – Improving Research capability in the Sri Lankan Higher Education sector.

2018 - 2019
TRANSFORM - Education reform project – Improving Research capability in the Sri Lankan Higher Education sector.
Funder: British Council | Value: £75,000

Mechanism of Chlamydia induced progesterone resistance

2018 - 2019
Chlamydia trachomatis is the most common sexually-transmitted infection in the world, and is associated with miscarriage, pre-term birth and infertility. However, the understanding of the mechanisms t...
Funder: Society for Reproduction and Fertility | Value: £12,034

Development of a UV-C hand-sanitiser unit

2017 - 2017
Development of a UV-C hand-sanitiser unit
Funder: Scottish Funding Council | Value: £5,000

The influence of ultramarathon running event on immune and cardiovascular systems

2017 - 2018
The project will measure circulating white blood cells and progenitor cells in response to an extreme exercise running bout/event/ We will also be quantifying upper respiratory tract symptoms.
Funder: British Association of Sport and Exercise Sciences | Value: £1,900