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73 results

Immunological homeostasis at the ovine placenta may reflect the degree of maternal foetal interaction

Journal Article
Wattegedera, S. R., Doull, L. E., Goncheva, M. I., Wheelhouse, N., Watson, D. M., Pearce, J., …Entrican, G. (2019)
Immunological homeostasis at the ovine placenta may reflect the degree of maternal foetal interaction. Frontiers in Immunology, 9, https://doi.org/10.3389/fimmu.2018.03025
Successful mammalian pregnancies are a result of complex physiological, endocrinological and immunological processes that combine to create an environment where the mother is ...

An acute dose of inorganic dietary nitrate does not improve high-intensity, intermittent exercise performance in temperate or hot and humid conditions

Journal Article
Smith, K., Muggeridge, D. J., Easton, C., & Ross, M. D. (2019)
An acute dose of inorganic dietary nitrate does not improve high-intensity, intermittent exercise performance in temperate or hot and humid conditions. European Journal of Applied Physiology, 119(3), 723-733. https://doi.org/10.1007/s00421-018-04063-9
Purpose: Dietary nitrate (NO3-) has repeatedly been shown to improve endurance and intermittent, high-intensity events in temperate conditions. However, the ergogenic effects...

Ferlavirus-related deaths in a collection of viperid snakes

Journal Article
Flach, E. J., Dagleish, M. P., Feltrer, Y., Gill, I. S., Marschang, R. E., Masters, N., …Wheelhouse, N. M. (2018)
Ferlavirus-related deaths in a collection of viperid snakes. Journal of Zoo and Wildlife Medicine, 49(4), 983-995. https://doi.org/10.1638/2017-0223.1
Between June and October 2013 26 snakes of six viperid species kept in two adjoining rooms died (n = 16) or were euthanized on medical (1) or welfare grounds (9). Two were fro...

Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry

Journal Article
Dancer, S. J., & Kramer, A. (2019)
Four Steps to Clean Hospitals: Look; Plan; Clean; and Dry. Journal of Hospital Infection, 103(1), e1-e8. https://doi.org/10.1016/j.jhin.2018.12.015
Background Now that cleaning and decontamination are recognised as integral to infection control, it is timely to examine the process in more detail. This is because cleaning ...

Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease

Journal Article
Hooper, K. M., Barlow, P. G., Henderson, P., & Stevens, C. (2019)
Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease. Inflammatory Bowel Diseases, 25(4), 661-671. https://doi.org/10.1093/ibd/izy380
Inflammatory Bowel Disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis, is characterised by chronic inflammation of the gastrointestinal tract. Aetiology...

Shining a light on ultraviolet-C disinfection: No golden promises for infection prevention

Journal Article
de Kraker, M. E. A., Harbarth, S., & Dancer, S. J. (2018)
Shining a light on ultraviolet-C disinfection: No golden promises for infection prevention. American Journal of Infection Control, 46(12), 1422-1423. doi:10.1016/j.ajic.2018.07.026
No abstract available.

Protracted diagnosis of ACNES: a costly exercise

Journal Article
Dancer, S. J., Macpherson, S. G., & de Beaux, A. C. (2018)
Protracted diagnosis of ACNES: a costly exercise. Journal of Surgical Case Reports, 2018(9), 1-3. https://doi.org/10.1093/jscr/rjy230
This case report summarizes the course of events leading to diagnosis and eventual repair of anterior cutaneous nerve entrapment syndrome (ACNES) in a 58-year-old female. The ...

Beware Biofilm! Dry biofilms containing bacterial pathogens on multiple healthcare surfaces; a multicentre study

Journal Article
Ledwoch, K., Dancer, S., Otter, J., Kerr, K., Roposte, D., Rushton, L., …Maillard, J. (2018)
Beware Biofilm! Dry biofilms containing bacterial pathogens on multiple healthcare surfaces; a multicentre study. Journal of Hospital Infection, doi:10.1016/j.jhin.2018.06.028
Background Wet biofilms associated with medical devices have been widely studied and their link with healthcare-associated infections (HCAIs) is well recognized. Little attent...

Antiviral therapeutic approaches for human rhinovirus infections

Journal Article
Casanova, V., Sousa, F. H., Stevens, C., & Barlow, P. G. (2018)
Antiviral therapeutic approaches for human rhinovirus infections. Future Virology, https://doi.org/10.2217/fvl-2018-0016
Human rhinoviruses (RV) are the primary etiological agent of the common cold. This infection can be mild and self-limiting in immunocompetent hosts, but can be associated wit...

Estimating excess length of stay due to healthcare-associated infections: A systematic review and meta-analysis of statistical methodology

Journal Article
Manoukian, S., Stewart, S., Dancer, S., Graves, N., Mason, H., McFarland, A., …Reilly, J. (2018)
Estimating excess length of stay due to healthcare-associated infections: A systematic review and meta-analysis of statistical methodology. Journal of Hospital Infection, https://doi.org/10.1016/j.jhin.2018.06.003
Background Healthcare-associated infection (HAI) affects millions of patients worldwide. HAI is associated with increased healthcare costs, owing primarily to increased hospit...

Date


31 results

False webs: Network to address the misinformation pandemic

2023 - 2025
Fake news (inaccurate information) peaked during the pandemic with around 46 000 daily Twitter posts containing false information (Lupi, 2020). In Europe over 70% people regularly encounter fake news ...
Funder: Royal Society of Edinburgh | Value: £19,931

Development of an in vitro suppression assay to assess functionality of therapeutic regulatory T cell for the treatment of rheumatoid arthritis

2023 - 2024
MRS Summer Studentship for ENU Undergrad student Martin Swapp - 8 weeks in duration over summer 2023
Funder: Medical Research Scotland | Value: £3,030

Medical Research Scotland Vacation Scholarship

2022 - 2023
Investigating the anti-metastatic potential of Honokiol by attenuating KISS1/ KISS1R signaling
Funder: Medical Research Scotland | Value: £2,160

Exploiting micofluidic devices for physiologically relavent drug screening against human pathogens

2022 - 2022
Undergraduate student summer project (8 weeks)
Funder: Medical Research Scotland | Value: £2,160

Enhancing the stability and the delivery of lactoferrin for prevention and/or treatment of covid-19 respiratory disease.

2022 - 2023
Lactoferrin (LF) is a glycoprotein which is widely contained in many secretory fluids, mainly milk but also saliva, tears, and nasal secretions. Many scientific reports supported an application of thi...
Funder: Royal Society | Value: £17,494

Does Residual Beta Cell Function and Exercise Offer Synergistic Protection Against Hyperglycaemic Induced Circulating Vasoprotective Dysfunction in Type 1 Diabetes?

2021 - 2022
For people with T1D, exercise is beneficial, potentially reducing the progression of diabetes-related complications. Many people (up to 80%) with T1D still release small amounts of insulin together wi...
Funder: Diabetes Research & Wellness Foundation

TB/COVID-19 co-infections within a 3D in vitro imaging system

2021 - 2022
TB/COVID-19 co-infections within a 3D in vitro imaging system
Funder: Animal Free Research UK | Value: £500

Developing an adoptive regulatory T cell therapy for the treatment of rheumatoid arthritis

2021 - 2024
The immune system contains a balance of cells that turn responses ‘on’ and those that turn it ‘off’. When this balance breaks down, inappropriate immune responses can attack healthy tissue...
Funder: Chief Scientists Office | Value: £229,020

Host Defence Peptides as novel modulators of autophagy in Inflammatory Bowel Disease

2019 - 2022
Increasing numbers of patients are diagnosed with inflammatory bowel disease (IBD) each year, both in the United Kingdom and worldwide. Most drugs in current use for the treatment of IBD target the im...
Funder: The Daphne Jackson Trust | Value: £83,167

EEID travel award: Understanding transmission dynamics for bacterial zoonoses in humans, goats and camels among pastoral communities in Northern Kenya

2019 - 2019
EEID travel award: Understanding transmission dynamics for bacterial zoonoses in humans, goats and camels among pastoral communities in Northern Kenya
Funder: Biotechnology and Biological Sciences Research Council | Value: £1,960