De novo design of novel protease inhibitor candidates in the treatment of SARS-CoV-2 using deep learning, docking, and molecular dynamic simulations
Arshia, A. H., Shadravan, S., Solhjoo, A., Sakhteman, A., & Sami, A. (2021)
De novo design of novel protease inhibitor candidates in the treatment of SARS-CoV-2 using deep learning, docking, and molecular dynamic simulations. Computers in Biology and Medicine, 139, Article 104967. https://doi.org/10.1016/j.compbiomed.2021.104967
The main protease of SARS-CoV-2 is a critical target for the design and development of antiviral drugs. 2.5 M compounds were used in this study to train an LSTM generative net...
Hardware Design for Autonomous Robot Evolution
Hale, M. F., Angus, M., Buchanan, E., Li, W., Woolley, R., Le Goff, L. K., …Tyrrell, A. M. (2020)
Hardware Design for Autonomous Robot Evolution. In 2020 IEEE Symposium Series on Computational Intelligence (SSCI) (2140-2147). https://doi.org/10.1109/SSCI47803.2020.9308204
The long term goal of the Autonomous Robot Evolution (ARE) project is to create populations of physical robots, in which both the controllers and body plans are evolved. The t...